DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment U2A and lrrc51

DIOPT Version :9

Sequence 1:	NP_610315.1	Gene:	U2A / 35713	FlyBaseID:	FBgn0033210	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	XP_009290232.1	Gene:	lrrc51 / 767801	ZFINID:	ZDB-GENE-060929-962	Length:	185	Species:	Danio rerio

Alignment Length:	110	Identity:	31/110 - (28%)
Similarity:	59/110 - (53%)	Gaps:	23/110 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    47 IDLSDNDLRKLDNLPHLPRLKCLLLNNNRILRISEGLEEAVPNLGSIILTGNNLQELSDLEPLVG 111
            :|||.|:::.:|::  |.:||.|.|                     :.|.|||:||||:::.|..
Zfish    74 LDLSFNEIKHIDSV--LTQLKELRL---------------------LYLHGNNIQELSEVDKLAV 115

  Fly   112 FTKLETICLLINPVSTKPNYREYMAYKFPQLRLLDFRKIKQKDRQ 156
            ...|.||.|..||:.::.:||.::....|.::::||..:.:::|:
Zfish   116 LPSLHTITLHGNPIVSERDYRAHLIATLPHVKMIDFSAVTKQERE 160

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
U2A	NP_610315.1	LRR_9	1..175	CDD:258718	31/110 (28%)
		leucine-rich repeat	22..43	CDD:275380
		LRR_4	46..81	CDD:289563	10/33 (30%)
		leucine-rich repeat	46..65	CDD:275378	6/17 (35%)
		leucine-rich repeat	66..89	CDD:275378	4/22 (18%)
		leucine-rich repeat	90..114	CDD:275378	9/23 (39%)
lrrc51	XP_009290232.1	LRR_8	69..129	CDD:290566	24/77 (31%)
		LRR_4	69..112	CDD:289563	18/60 (30%)
		leucine-rich repeat	71..93	CDD:275380	7/20 (35%)
		leucine-rich repeat	94..118	CDD:275380	11/44 (25%)
		leucine-rich repeat	119..145	CDD:275380	8/25 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1447031at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.820