DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment U2A and Lrrc51

DIOPT Version :9

Sequence 1:	NP_610315.1	Gene:	U2A / 35713	FlyBaseID:	FBgn0033210	Length:	265	Species:	Drosophila melanogaster
Sequence 2:	NP_001099754.1	Gene:	Lrrc51 / 293156	RGDID:	1565856	Length:	192	Species:	Rattus norvegicus

Alignment Length:	162	Identity:	42/162 - (25%)
Similarity:	65/162 - (40%)	Gaps:	47/162 - (29%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 DLRGYK--IPQI----ENLGATLDQFDTIDLSDNDLRKLDNLPHLPRLKCLLLNNNRILRISEGL 83
            ||:.:.  :.|:    |||.       .||||.|||..:|     |.|....
  Rat    63 DLKDFNQVVSQLLQHPENLA-------WIDLSFNDLTTID-----PVLTTFF------------- 102

  Fly    84 EEAVPNLGSIILTGNNLQELSDLEPLVGFTKLETICLLINPVSTKPNYREYMAYKFPQLRLLDFR 148
                 ||..:.|.||::..|.::..|....:|.::.|..||:..:..||:|:....|::...||.
  Rat   103 -----NLSVLYLHGNSIHRLGEVNKLAVLPRLRSLTLHGNPIEEEKGYRQYVLCNLPRITTFDFS 162

  Fly   149 KIKQKDRQAAQEF---------FRTKQGKDVL 171
            .:.:.||..|:.:         .|.||  |||
  Rat   163 GVTKADRSTAEVWKRMNIKPKKVRIKQ--DVL 192

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
U2A	NP_610315.1	LRR_9	1..175	CDD:258718	42/162 (26%)
		leucine-rich repeat	22..43	CDD:275380	6/23 (26%)
		LRR_4	46..81	CDD:289563	10/34 (29%)
		leucine-rich repeat	46..65	CDD:275378	8/18 (44%)
		leucine-rich repeat	66..89	CDD:275378	1/22 (5%)
		leucine-rich repeat	90..114	CDD:275378	6/23 (26%)
Lrrc51	NP_001099754.1	LRR 1	49..71		2/7 (29%)
		leucine-rich repeat	52..80	CDD:275380	3/16 (19%)
		LRR 2	80..101		12/32 (38%)
		leucine-rich repeat	81..103	CDD:275380	11/51 (22%)
		LRR_9	<89..173	CDD:405295	25/106 (24%)
		LRR 3	103..124		6/20 (30%)
		leucine-rich repeat	104..128	CDD:275380	6/23 (26%)
		leucine-rich repeat	129..155	CDD:275380	7/25 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1644
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1447031at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820