DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rpt1 and RPT4

DIOPT Version :10

Sequence 1:NP_477473.1 Gene:Rpt1 / 35701 FlyBaseID:FBgn0028687 Length:433 Species:Drosophila melanogaster
Sequence 2:NP_014902.3 Gene:RPT4 / 854433 SGDID:S000005785 Length:437 Species:Saccharomyces cerevisiae


Alignment Length:425 Identity:170/425 - (40%)
Similarity:244/425 - (57%) Gaps:47/425 - (11%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 LGDDQRKVKHDEKEDKEIKSLDEGDIELLKTYGQSQYHKSIKSIEEDIQKAVKQVNELTGIKESD 69
            |...:||:....:.|.::|...:...:|.|.|.::         |.|| ||::.:.:|.|     
Yeast    57 LNQFKRKLLEHRRYDDQLKQRRQNIRDLEKLYDKT---------ENDI-KALQSIGQLIG----- 106

  Fly    70 TGLAPPALWDLAADKQILQNEQPLQVARCTKIINADSDDPKYIINVKQFAKFVVDLADSVAPTDI 134
                 ..:.:|:.:|.|::                .|..|:||:.|:          :||..:.:
Yeast   107 -----EVMKELSEEKYIVK----------------ASSGPRYIVGVR----------NSVDRSKL 140

  Fly   135 EEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEDKPDVTYSDVGGCKEQIEKLREVVETPLLHPE 199
            ::|:||.:|.....|...||.:.||.|..|...::.::|:..:||..|||.:||||:|.||.:||
Yeast   141 KKGVRVTLDITTLTIMRILPRETDPLVYNMTSFEQGEITFDGIGGLTEQIRELREVIELPLKNPE 205

  Fly   200 KFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRVIGSELVQKYVGEGARMVRELFEMA 264
            .|..:||:|||||||:|||||||||.|:|||....|.||....|.:|.||:||.||::||:|..|
Yeast   206 IFQRVGIKPPKGVLLYGPPGTGKTLLAKAVAATIGANFIFSPASGIVDKYIGESARIIREMFAYA 270

  Fly   265 RSKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQLDGFDPRGNIKVLMATNRPDTLDP 329
            :..:.|:||.||:|||||.||.:|...|.|:|||::||:.|:||||..|..|::|||||||||||
Yeast   271 KEHEPCIIFMDEVDAIGGRRFSEGTSADREIQRTLMELLTQMDGFDNLGQTKIIMATNRPDTLDP 335

  Fly   330 ALMRPGRLDRKVEFGLPDQDGRSHIFKIHARSMSVERDIRFDLLARLCPNSTGAEIRSVCTEAGM 394
            ||:||||||||||..||::.||..|||||...:....:..|:...::.....||:||:..||||.
Yeast   336 ALLRPGRLDRKVEIPLPNEAGRLEIFKIHTAKVKKTGEFDFEAAVKMSDGFNGADIRNCATEAGF 400

  Fly   395 FAIRARRKVATEKDFLEAVKKVIKSYAKFSATPRY 429
            ||||..|......|.::||:||.: ..|...|..|
Yeast   401 FAIRDDRDHINPDDLMKAVRKVAE-VKKLEGTIEY 434

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rpt1NP_477473.1 PRK03992 88..430 CDD:179699 152/342 (44%)
RPT4NP_014902.3 PRK03992 66..433 CDD:179699 166/413 (40%)

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