DRSC/TRiP Functional Genomics Resources

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Protein Alignment Rpt1 and Psmc3

DIOPT Version :10

Sequence 1:NP_477473.1 Gene:Rpt1 / 35701 FlyBaseID:FBgn0028687 Length:433 Species:Drosophila melanogaster
Sequence 2:NP_032974.2 Gene:Psmc3 / 19182 MGIID:1098754 Length:442 Species:Mus musculus


Alignment Length:449 Identity:176/449 - (39%)
Similarity:256/449 - (57%) Gaps:60/449 - (13%)


- Green bases have known domain annotations that are detailed below.


  Fly     3 DYLGDDQRKVKHDE------KEDKEIKSLDEGDIELLKTYGQSQYHKSIKSIEEDIQK------- 54
            |.:|::..|:..:|      ..|.|||.:..   |:|:...:.|..|.  .|:|:.:|       
Mouse    30 DGIGEEVLKMSTEEIVQRTRLLDSEIKIMKS---EVLRVTHELQAMKD--KIKENSEKIKVNKTL 89

  Fly    55 --AVKQVNELTGIKESDTGLAPPALWDLAADKQILQNEQPLQV-------ARCTKIINADSDDPK 110
              .|..|.||..:..:|                  |.|....:       .:|..|  ..|....
Mouse    90 PYLVSNVIELLDVDPND------------------QEEDGANIDLDSQRKGKCAVI--KTSTRQT 134

  Fly   111 YIINVKQFAKFVVDLADSVAPTDIEEGMRVGVDRNKYQIHIPLPPKIDPTVTMMQVEDKPDVTYS 175
            |.:.|..    :|| |:.:.|.|:     |||:::.|.|...||.:.|..|..|:|:::|...||
Mouse   135 YFLPVIG----LVD-AEKLKPGDL-----VGVNKDSYLILETLPTEYDSRVKAMEVDERPTEQYS 189

  Fly   176 DVGGCKEQIEKLREVVETPLLHPEKFVNLGIEPPKGVLLFGPPGTGKTLCARAVANRTDACFIRV 240
            |:||..:||::|.|.:..|:.|.|||.||||:||||||::|||||||||.|||.|.:|.|.|:::
Mouse   190 DIGGLDKQIQELVEAIVLPMNHKEKFENLGIQPPKGVLMYGPPGTGKTLLARACAAQTKATFLKL 254

  Fly   241 IGSELVQKYVGEGARMVRELFEMARSKKACLIFFDEIDAIGGARFDDGAGGDNEVQRTMLELINQ 305
            .|.:|||.::|:||::||:.|.:|:.|...:||.||:||||..|||....||.|||||||||:||
Mouse   255 AGPQLVQMFIGDGAKLVRDAFALAKEKAPSIIFIDELDAIGTKRFDSEKAGDREVQRTMLELLNQ 319

  Fly   306 LDGFDPRGNIKVLMATNRPDTLDPALMRPGRLDRKVEFGLPDQDGRSHIFKIHARSMSVERDIRF 370
            ||||.|...:||:.||||.|.|||||:|.||||||:||.:|:::.|:.|.:||:|.|:|..|:.:
Mouse   320 LDGFQPNTQVKVIAATNRVDILDPALLRSGRLDRKIEFPMPNEEARARIMQIHSRKMNVSPDVNY 384

  Fly   371 DLLARLCPNSTGAEIRSVCTEAGMFAIRARRKVATEKDFLEAVKKVIKSYAKFSATPRY 429
            :.|||...:..||:.::||.||||.|:|......|.:|::|.:.:|   .||..|..:|
Mouse   385 EELARCTDDFNGAQCKAVCVEAGMIALRRGATELTHEDYMEGILEV---QAKKKANLQY 440

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Rpt1NP_477473.1 PRK03992 88..430 CDD:179699 156/349 (45%)
Psmc3NP_032974.2 PRK03992 42..435 CDD:179699 171/430 (40%)

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