DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1603 and Zfp335

DIOPT Version :10

Sequence 1:NP_610290.2 Gene:CG1603 / 35683 FlyBaseID:FBgn0033185 Length:586 Species:Drosophila melanogaster
Sequence 2:XP_030107665.1 Gene:Zfp335 / 329559 MGIID:2682313 Length:1338 Species:Mus musculus


Alignment Length:656 Identity:128/656 - (19%)
Similarity:217/656 - (33%) Gaps:236/656 - (35%)


- Green bases have known domain annotations that are detailed below.


  Fly    47 DEDVRINEIKEDTEELYSVVDAADPAIAYGPDEFFEVIENSNGVDQWMEADSKDIQYEEDATAWS 111
            |..:.:::....:.:|.|.:|              ::||::.|.|.        ||        |
Mouse   113 DPSMLVSDCTASSSDLGSAID--------------KIIESTIGPDL--------IQ--------S 147

  Fly   112 AATNNSWEFGPGGSSLELPAGKEVTQMDESSQNHIPLNTDDDDVDCSDFFMSEDDLAPPRKPGRP 176
            ..|..|.|.|          |.|.||       ::.|...||....:. .||...||        
Mouse   148 CITVTSGEEG----------GAETTQ-------YLILQGPDDGAPMAS-SMSTSTLA-------- 186

  Fly   177 PRRTRPGQVFKFKVSFIRSNPRVLHLIQAYKEHP-----CLWNPSDEHYQDEPARSMAYE---AI 233
                                 ..|..|:|..:.|     ||..|  |..|.:|: |:|.:   .:
Mouse   187 ---------------------NSLAAIEALADGPTSTSACLEPP--EEPQGDPS-SVAQQPPAPV 227

  Fly   234 MERMDRKANVLFTVEELKKTLEQLHVQYTLALETKQRGKLVGLAARYFAKCEF----LSVAPVVT 294
            .|.:|        ::.|:..:|.:.||.......:.|........|:..:..|    |:.|...|
Mouse   228 TEELD--------LQSLEAMMEVVVVQQFKCKMCQYRSSTKATLLRHMRERHFRPAALAAAAAAT 284

  Fly   295 --------------------PRENEEDNDLT-AIKLNFKEEN----------------------- 315
                                |.|.|||:|:. |..::..||:                       
Mouse   285 GKRGRVRKWGTSTKTTEEDRPEEEEEDDDIVDAGAIDDLEEDSDYNPAEDEPRGRQLRLQRPTPS 349

  Fly   316 ---------------LITTSFIETYANYPVLYNQAL---PDFGSIEI-RADAFKRMAKEFQPVVK 361
                           .:.||.:......|::.:|:.   |:...:|. .:...:.:.|..:.:|:
Mouse   350 TPRPRRRPGRPRKLPRLETSDLHDGVGQPLVSSQSTQSPPELQDLEAPSSSGLRALGKVGRGLVE 414

  Fly   362 A--NETDVYIAV-----------------------NKLRRWLYDAIRRLKSKELIQKCSKQEVQY 401
            :  :::|...|.                       .|.|::.|.:     .|.|::       .|
Mouse   415 SGVSQSDAENAAPSCQDEADAPPRRRGRPSRRFLGKKYRKYYYKS-----PKPLLR-------PY 467

  Fly   402 LQMCSFLPAKGSESQVLYCDYCDKRFHGDYNLRVHIVKAHEVGDLPYL--CSFCPRRFDRHVDMD 464
            |                 |..|..||....:||.| |.:||.|| |.|  |..|..|..|...:.
Mouse   468 L-----------------CRICGSRFLSHEDLRFH-VNSHEAGD-PQLFRCLQCSYRSRRWSSLK 513

  Fly   465 RHKLRSHFERKLKCQYCEKSFAVDTDLKVHTLIHTGER-------PHV----CDICGKTFRLKLL 518
            .|.......:..||..|..:.....|:..|..:|:.:|       |.:    |.:||:.:.::..
Mouse   514 EHMFNHVGSKPYKCDECSYTSVYRKDVIRHAAVHSQDRKKRPDPTPKLSSFPCPVCGRVYPMQKR 578

  Fly   519 LDHHVNGVHLNIRPYSCNMCTKTFRKKFELANHIKGHLNI---RDKKCEYCDATFYDHSSLSRHR 580
            |..|:. .|...:|:.|:.|.|:|:|::....|:..|:..   |..|||:|:....|..:|..|:
Mouse   579 LTQHMK-THSTEKPHMCDKCGKSFKKRYTFKMHLLTHIQAVANRRFKCEFCEFVCEDKKALLNHQ 642

  Fly   581 RSHRSE 586
            .||.|:
Mouse   643 LSHVSD 648

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
CG1603NP_610290.2 MADF_DNA_bdg 202..287 CDD:463144 20/96 (21%)
MADF_DNA_bdg 321..408 CDD:463144 15/115 (13%)
C2H2 Zn finger 420..441 CDD:275368 8/20 (40%)
COG5048 <424..583 CDD:227381 47/174 (27%)
C2H2 Zn finger 450..471 CDD:275368 5/20 (25%)
C2H2 Zn finger 478..498 CDD:275368 4/19 (21%)
C2H2 Zn finger 506..527 CDD:275368 5/20 (25%)
C2H2 Zn finger 535..555 CDD:275368 6/19 (32%)
C2H2 Zn finger 563..583 CDD:275368 6/19 (32%)
Zfp335XP_030107665.1 C2H2 Zn finger 469..489 CDD:275368 8/20 (40%)
C2H2 Zn finger 499..519 CDD:275368 5/19 (26%)
zf-H2C2_2 511..536 CDD:463886 4/24 (17%)
zf-H2C2_5 525..548 CDD:404746 5/22 (23%)
C2H2 Zn finger 527..547 CDD:275368 4/19 (21%)
C2H2 Zn finger 566..586 CDD:275368 5/20 (25%)
zf-H2C2_2 578..603 CDD:463886 8/25 (32%)
C2H2 Zn finger 594..614 CDD:275368 6/19 (32%)
C2H2 Zn finger 625..645 CDD:275368 6/19 (32%)
C2H2 Zn finger 653..674 CDD:275368
C2H2 Zn finger 682..701 CDD:275368
C2H2 Zn finger 1022..1042 CDD:275368
SFP1 <1027..1127 CDD:227516
C2H2 Zn finger 1050..1070 CDD:275368
zf-H2C2_5 1076..1100 CDD:404746
C2H2 Zn finger 1078..1098 CDD:275368
zf-H2C2_2 1090..1115 CDD:463886
C2H2 Zn finger 1106..1127 CDD:275368
Blue background indicates that the domain is not in the aligned region.

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