DRSC/TRiP Functional Genomics Resources

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Protein Alignment az2 and CG12219

DIOPT Version :10

Sequence 1:NP_610289.2 Gene:az2 / 35682 FlyBaseID:FBgn0025185 Length:593 Species:Drosophila melanogaster
Sequence 2:NP_572312.1 Gene:CG12219 / 31572 FlyBaseID:FBgn0043796 Length:562 Species:Drosophila melanogaster


Alignment Length:529 Identity:105/529 - (19%)
Similarity:153/529 - (28%) Gaps:192/529 - (36%)


- Green bases have known domain annotations that are detailed below.


  Fly    14 EHFVLACAHQND----C-YVEMEFKRWREFIVHVK-----------EHLEANPSMQQELTTSEVI 62
            ||.   ..|..|    | |.||.|:.......|||           |..:|..|.|...|     
  Fly   155 EHI---ATHTGDRPIACPYCEMAFRCRSNMYTHVKSKHTTQWLKAREERDAAKSNQNHTT----- 211

  Fly    63 SSAKCEEEVSPAKVFIVEEPPENCLAEDMFVDVPPSSENDESTSPVEEEEEEDDEVDSSSMTVDC 127
                 .||.:|| |.:....|...||.      .|:|    |.||............:||.|...
  Fly   212 -----PEETAPA-VLVPVPAPAPALAS------APAS----SASPGNTVNPAATATPASSATPTT 260

  Fly   128 ELGTRNSTHFAPLTKFNPTFYRRSPRITQFIELYKQQTCLWDPADESYRDKEKRANAYEELLEQL 192
            .|..      |||.         ||...|.:.|                         ..:..|.
  Fly   261 NLAA------APLP---------SPPTVQQLPL-------------------------SVIKSQP 285

  Fly   193 KATVNLHLTAYKLKKCITSLHAQYASISRQKKTQKLTKVPLYYHGKYSFLAERGSLEDADSDDVD 257
            ...:||.:|     |...|......:.|.::||....||.              ..|.:|..|.|
  Fly   286 SEAMNLTIT-----KTPPSGSRGSRNRSSRRKTHSPKKVQ--------------HTEGSDVSDED 331

  Fly   258 GDGK----IKLVFTEENQLTTQFI---DLYSKFPQLYDPAHKHFCNLNVRKSSLIEITDLLTSEF 315
            ...|    .:|:....|.:....:   .|....|...|...:..|      :||::         
  Fly   332 SPQKRLKENELILANYNAVAAAVVAAASLTGNPPGQPDSLQQRLC------ASLLQ--------- 381

  Fly   316 SLGLVTHYDVYDSIQSMRQWYSRRIKTLTDVQCVGLSLAEKQYIERCNSFMPTKSFRQKLKCEVC 380
                         .|...|.::....|......||.|.|...                       
  Fly   382 -------------QQHQEQLFAVMSATAAAAAAVGTSSATTT----------------------- 410

  Fly   381 EHSFSTDHALQAHQFRDHKMGDGGWFRCTLCELNFDRK--CHLQQ--HSQRVHMDKSFVCEICSR 441
              :.:|...:.||.:.:|...:            .|::  ..||.  |:..|    |.:|..|..
  Fly   411 --TTTTTGTMMAHPYGNHPPSE------------TDKRPAAPLQAVIHAAPV----SIICPNCGE 457

  Fly   442 SFAFGNQLAIHKRTHDEKHVAKP-FVCEFCGKCFKQKIQMTTHVTAVHTKIRAFKCDMCPKDFLT 505
                     :..:.|  :.::|| :.|:.|||.||.|..:..|. |.||.::...|..||.:|.:
  Fly   458 ---------LPGQNH--RCLSKPKYACDVCGKSFKMKRYLEEHF-ATHTGVKLHTCAFCPTEFRS 510

  Fly   506 KRDLKDHVK 514
            |.::..|.|
  Fly   511 KSNMYHHTK 519

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
az2NP_610289.2 MADF_DNA_bdg 157..242 CDD:463144 12/84 (14%)
MADF_DNA_bdg 276..>341 CDD:463144 8/67 (12%)
C2H2 Zn finger 377..398 CDD:275368 3/20 (15%)
C2H2 Zn finger 408..429 CDD:275368 4/24 (17%)
C2H2 Zn finger 436..456 CDD:275368 2/19 (11%)
C2H2 Zn finger 467..488 CDD:275368 9/20 (45%)
C2H2 Zn finger 496..516 CDD:275368 7/19 (37%)
C2H2 Zn finger 524..544 CDD:275368
C2H2 Zn finger 551..572 CDD:275368
CG12219NP_572312.1 zf-AD 2..91 CDD:214871
PHA00733 <117..189 CDD:177301 12/36 (33%)
C2H2 Zn finger 140..160 CDD:275368 2/7 (29%)
zf-H2C2_2 152..177 CDD:463886 9/24 (38%)
C2H2 Zn finger 168..186 CDD:275368 6/17 (35%)
C2H2 Zn finger 473..493 CDD:275370 9/20 (45%)
C2H2 Zn finger 501..522 CDD:275370 7/19 (37%)
Blue background indicates that the domain is not in the aligned region.

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