Protein Alignment CG11141 and hps5

DIOPT Version :10

• Sequence 1: NP_610282.1
• Gene: CG11141 / 35672
• FlyBaseID: FBgn0033177
• Length: 710
• Species: Drosophila melanogaster
• Sequence 2: NP_001083008.3
• Gene: hps5 / 100037388
• ZFINID: ZDB-GENE-070410-80
• Length: 1133
• Species: Danio rerio
• Alignment Length: 801
• Identity: 173/801 - (21%)
• Similarity: 294/801 - (36%)
• Gaps: 248/801 - (30%)

  Fly    26 RLQRGFFPANLNLTCVDATEEFLAMGSDAGIVFWYNRHTGEMQKL----KAEVATRITCVRVVNS 86
            ||..|    .:..||:..:.::||:|:.||.:....| .|..|||    |....|:::|   ...
Zfish    28 RLDSG----RIKCTCLSVSRKWLALGTSAGGLHLIQR-DGWKQKLILTHKEGSITQVSC---CPH 84

  Fly    87 VEYMVAAGCANGQVSIFQIQKELPRDLDLVAPCTKSRPIERYTIRDLHK--CVVSCCEWSKNGMK 149
            .|..:|...:.|.|.::::..|           .:.|| ||.::...|:  .|.|.| |....::
Zfish    85 DEDFIAVATSQGLVVVWELHLE-----------RRGRP-ERASVSWEHRGVTVTSLC-WDTVALR 136

  Fly   150 LYSGDRQGVVVLTELDYQAHLSKS-------VEILSEA-YEIVQLSVRQSYLLVATLYRCIVCQM 206
            :::||..|.|...... .:.|.|.       |:.::.. ..:|||.....:|::::|.||.:|
Zfish   137 VFAGDVGGKVSCVRAG-SSKLGKGSAFVIFPVQTITTVDSRVVQLGYTDGHLVISSLSRCYLC-- 198

  Fly   207 DAQTSQWNITQVGKKDRKQLIDCGAIFLKKQEANK---------PQLVCGRPGLRFWVADAAGNV 262
              .|.:....:||.|:|..  :.||.||.:..|.:         |.|.|.|||.|.|.|..:|.|
Zfish   199 --DTEREKFWRVGNKERDG--EFGACFLTQGLAGQRGQLVGCPAPLLFCARPGSRIWEASFSGEV 259

  Fly   263 SKTVIFRDAVLRSPTWEIPILNPKQRSEPSGTHHTSASTSSTRHSGLADGDVGYVASSNFRQLYL 327
            ..|..|:..:...|   :|:::.|  :||   |.....|:.              .|..|.:|..
Zfish   260 LSTHQFKQLLAVPP---LPLVSCK--NEP---HFNPTQTNP--------------QSLAFPRLLQ 302

  Fly   328 YDGHDSLLVTHDDATLYVLNLDRLKVEAVARGLRKILDFCVCGKEIFVLEGNRTLLRLAPLPEPP 392
            :.  |..|:|..|:.:|:......:| .:...::.:|:..|...::|.|.|:..|
Zfish   303 FG--DQNLLTWTDSAIYIFTPHSGQV-LLWTEVKDVLEISVFRNDLFCLHGDGRL---------- 354

  Fly   393 NKTAKVIFNPLMPPPVPVLGSHLSQLESPIELQAEPVLQNAEECFE-LSPVEQLNLNVPIEIAVE 456
                                ||:| |.||            :.|.| |...|...:...:....:
Zfish   355 --------------------SHMS-LVSP------------DRCVERLMKRENWTIAATVCCMFQ 386

  Fly   457 SPLTQQNRR--LEIFR---------------RIGEMDFEQSIVH------TTRKTSVGKPPEASG 498
            ..:|....|  |.|.|               .||:::...|.:.      ::|::|:.. .|:..
Zfish   387 HAITTSKARKSLSIDRLEHLKAQLNSTSHQQLIGQLEEVISKLEPLDSACSSRRSSISS-HESFN 450

  Fly   499 V---GIVEI----GHETHELRLPLTNAA-----TLMEASYCQME--NNGLAS------------- 536
            |   ||..:    |.::.:....|.|.:     .|.|.|:.:.|  :|..||
Zfish   451 VLDCGIYRVISRRGSQSDDDASSLANQSMFEEERLKEFSFTEEEQVDNDSASVRGEGDRSDLGLQ 515

  Fly   537 --PLDMKA----AFLQHLPDALSPTTLQKTVAEKAKTLAAELDL---PEVH----------LAPL 582
              ||..::    ..||.:.|::|  :..|...||..||....||   |::.          .:|:
Zfish   516 FLPLPFRSKPPRVALQAVRDSVS--SFMKKTTEKINTLQMNADLWPRPDLREGVQGEVASTASPI 578

  Fly   583 SQE--------------ELHAVQAQT----PQISDPLIRCYPTHLEEASIQTSS-RENATNPADD 628
            |:|              ||..::|.|    .||.||::...|..|.:...:.:. .|.|..|.|
Zfish   579 SEESEQELNTEHSGSESELLELRAATKKAISQIQDPMVLLDPLCLSDVLQEWAPVLERALGPED- 642

  Fly   629 YHVGEPVDGIRSFGVSKRKMAPLKFVLSQPKPTLKLEENRDDEEYTSFL-------PDFRR--AG 684
                              ::.|::  .:.|:     |:..::||..|.:       |:...  |.
Zfish   643 ------------------QILPVE--TTNPE-----EKTLEEEELVSSMSCCVVVQPEISTSPAA 682

  Fly   685 DP--LAIHKETPATSDSNTSS 703
            ||  .|.|.|....|:|...|
Zfish   683 DPDESATHTEEEDFSESTPCS 703

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG11141	NP_610282.1	WD40 repeat	138..188	CDD:293791	13/57 (23%)
		WD40 repeat	194..228	CDD:293791	9/33 (27%)
hps5	NP_001083008.3	None