DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment fa2h and faxdc2

DIOPT Version :9

Sequence 1:	NP_610279.3	Gene:	fa2h / 35670	FlyBaseID:	FBgn0050502	Length:	355	Species:	Drosophila melanogaster
Sequence 2:	NP_998672.1	Gene:	faxdc2 / 406828	ZFINID:	ZDB-GENE-040426-2907	Length:	323	Species:	Danio rerio

Alignment Length:	156	Identity:	36/156 - (23%)
Similarity:	51/156 - (32%)	Gaps:	55/156 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   206 LLWSFLEYTLHRWVFHVKLSNKSGSWLCTFHFMIHGLHHKVPFDPMRLVFPPLPGAVLAAVIYTP 270
            |:...|.|..||.|.|..|           :..||.:||:.          ..|..|:|...: |
Zfish   169 LMEEILFYYTHRLVHHPSL-----------YKSIHKIHHEW----------TAPVGVVALYAH-P 211

  Fly   271 LSFVLSHPRVILSGALAGYLCYDMMHYYLHYGNPSLWAFV------------HM-----KRYHHH 318
            :..|||:    :..||.|.|....     |....|||..:            |:     ..:|.:
Zfish   212 VEHVLSN----MLPALIGPLLLGS-----HVSTTSLWFTIALLVTTVSHCGYHLPLLPSPEFHDY 267

  Fly   319 HHFSHQTLGYGISSPLWDVVFKTRIH 344
            ||...... ||:...|      .|:|
Zfish   268 HHLKFNQC-YGVLGVL------DRLH 286

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
fa2h	NP_610279.3	Cyt-b5	6..73	CDD:278597
fa2h	NP_610279.3	FA_hydroxylase	117..341	CDD:294712	34/151 (23%)
faxdc2	NP_998672.1	ERG3	<159..288	CDD:225546	36/156 (23%)
faxdc2	NP_998672.1	FA_hydroxylase	164..288	CDD:282034	36/156 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3000
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900