Protein Alignment Br140 and jade2

DIOPT Version :10

• Sequence 1: NP_610266.1
• Gene: Br140 / 35648
• FlyBaseID: FBgn0033155
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: XP_697831.5
• Gene: jade2 / 569359
• ZFINID: ZDB-GENE-120215-66
• Length: 795
• Species: Danio rerio
• Alignment Length: 874
• Identity: 232/874 - (26%)
• Similarity: 371/874 - (42%)
• Gaps: 204/874 - (23%)

  Fly   111 SARQYANPESLVSYNEEEATVTFNLDGKSVRLGIDDALPLVEDEEFAALVARGCILNADAPPLEE 175
            |::......:.|.:.::..:..|..|..:. :.:.|:..|..||.:..     |
Zfish    30 SSKNTGTSSTWVRHEQKRPSEVFRTDFITA-MKLPDSAQLSADEFYIL-----C----------- 77

  Fly   176 NAPWAR-----VQVPVARVAEIPDYRVSDAPP-RPLAYYRFIE-KSLEELDGEV-EYDVDEEDSA 232
             .||.:     |||| |.|..||:..|...|. ..:.::..:: :|..|:...: .||:|:.|.|
Zfish    78 -DPWRQEWEKGVQVP-ANVETIPEPVVRMLPEVSRIPFFSAVQTRSQSEISEPLSRYDLDDLDVA 140

  Fly   233 WLEHMNEERQRLGLNAVGIDTMELLMDRLEK---ESHFQAAANGTPTGVEVDDDAVCCICLDGEC 294
            |||.:|.|.::|.|..:...|||.|:..||:   ::..|...|....|:|.|:|.||.:|...|.
Zfish   141 WLELVNAEFRQLALPELDELTMEQLLVELERRCQQNMQQQIENQEGLGIEYDEDVVCDVCRSPEG 205

  Fly   295 QNTNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRRC---LQSPSKPVNCVLCPNAGGAFKQTDHG 356
            ::.|.::|||.||:.|||.|||:..:|:|.||||.|   :||     .|:|||..|||.|.|..|
Zfish   206 EDGNEMVFCDNCNVCVHQACYGILKVPQGNWLCRTCALGVQS-----KCLLCPRRGGALKPTRSG 265

  Fly   357 -QWAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFH 420
             :|.||.||||||||.......:|||..:..||.:||.|:|.:|.|.. |.||||...||..|||
Zfish   266 TKWVHVSCALWIPEVSIGCPEKMEPITKVSHIPASRWALSCSLCCEHS-GTCIQCSMPSCTVAFH 329

  Fly   421 VTCAQQAGLYMTMDTVKDGHNDSSMHVQKFAYCHAHTP-----ADAKLKMNVPDFEDTRH----- 475
            ||||...||.| ..|:.|  ||   .|:..:||..|:.     :...::.:.|   |.||
Zfish   330 VTCAFDHGLEM-RTTLAD--ND---EVRFKSYCLEHSSVWRSNSSGGVQSDRP---DPRHAVPDP 385

  Fly   476 ----KMKEARKALAKKRSTAPVVLIPTIPPDRVQEIA----TMVTMQRKKEFL-------DRIIA 525
                |.::|.:..|.:|.            .::||:.    |:|..:...|.|       |.:..
Zfish   386 AAAQKQEQAEREKASQRK------------QKLQELEDEFYTLVDPKDIAESLSLPDAHVDFLFQ 438

  Fly   526 YWTLKRHYRNGVPLLRRLQSQGNNHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCEL 590
            ||.|:|......||:...:.:.:|  :.|:       :...|||:||.:..|||||||.|.||.:
Zfish   439 YWKLRRKTNGNKPLVSMKRDEVDN--LAQQ-------EQDVLYRRLKLFTHLRQDLERVRNLCCM 494

  Fly   591 VRKREKLKVAFVRISEEVVMLQLNPLEAALNKLLDALEARDSMQIFREPVDTSEVPDYTDIVKQP 655
            :.:|||:|.:...:.|::..||:..:|                               .::|.:.
Zfish   495 ITRREKIKHSLCNLQEKIFSLQIQLME-------------------------------QNLVGEK 528

  Fly   656 MDLG------TMRAKLKECQYNSLEQLEADFDLMIQNCLAYNNKDTVFYRAGIRMRDQAAPLFVQ 714
            ...|      .::.::||.:.||.|:                 ||        :.|.....||.|
Zfish   529 SQRGERKHRNRVQERVKERRKNSPEK-----------------KD--------KWRSDDNSLFSQ 568

  Fly   715 V--RKELQRDGLLARSQRYHVDHVEAEVEQELRLLLAAPASEGIVQKLLILADKSQVLKNPTYRT 777
            :  .:....||.|..|.:....|:.|| ....|..|:|...|   ....:|:|  |:|:.    .
Zfish   569 LGFSRSFPIDGSLFDSWQAQSIHISAE-SMLSRWSLSAGTPE---TSASLLSD--QLLRG----E 623

  Fly   778 KKIKQIRLEISRMRKSLQKARFAARHSSHANQSQSDDEDTLGGSPSKKR---TRKRFNSSGVDME 839
            :.:..:.:: |.|:.:.:..|...:|...|.:|:   ..||...|:|.:   |.:|       ..
Zfish   624 ESLLSLMMD-SSMQNTWKTPRLGRKHPKSAPRSR---RKTLCSPPAKGKVCVTERR-------CR 677

  Fly   840 LGHDDDDEEEDSDEDSMGEDTVSKDLLNSTQTPPCSPIKSLNNSSSPVGINRRTAILLTRKAQAA 904
            .|...:|.:..||                .::.|..|..:..:|..   |:.....:|.:::|.:
Zfish   678 RGEKTEDFQRSSD----------------GRSDPLQPAIAKMDSCH---ISEERDSVLEKRSQKS 723

  Fly   905 LKR--PSEPLTTPVKEEQHNSQSSNTQST 931
            ::.  |.:..|....:...:|..|||..|
Zfish   724 VRMHLPRQSKTRCKSQTVESSVQSNTPDT 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_610266.1	SFP1	<22..61	CDD:227516
		COG5141	203..>625	CDD:227470	154/455 (34%)
		Bromo_brd1_like	615..712	CDD:99944	11/102 (11%)
		MSCRAMM_ClfA	<1080..1163	CDD:468110
		PWWP_BRPF	1303..1414	CDD:438964
jade2	XP_697831.5	COG5141	107..>515	CDD:227470	151/443 (34%)
		ePHD_JADE2	249..359	CDD:277175	56/116 (48%)