Protein Alignment Br140 and rno

DIOPT Version :10

• Sequence 1: NP_610266.1
• Gene: Br140 / 35648
• FlyBaseID: FBgn0033155
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: NP_612007.2
• Gene: rno / 38027
• FlyBaseID: FBgn0035106
• Length: 3241
• Species: Drosophila melanogaster
• Alignment Length: 1639
• Identity: 375/1639 - (22%)
• Similarity: 564/1639 - (34%)
• Gaps: 573/1639 - (34%)

  Fly    39 GLQYHLMKYDHDNPQ-----PLTPVLTPS-RKKARSRSGGHHST-------------------PR 78
            |.|.|...: |..||     .:.|...|: |:|.|..:|...:.                   |.
  Fly     8 GNQQHHQSH-HPPPQQHQRKDVEPQPPPTKRRKGRPPNGATTAAVAEVTGSGPATGSERVPVLPL 71

  Fly    79 PHKDHPTPG---GGGAEARNGCSSASA------------------GGGSASGVSARQYANPESLV 122
            ....|..||   |||.:.|....:.|.                  |..|:|...||..|:.:...
  Fly    72 CKSKHEEPGAEAGGGGQGRAAAGATSTSKSKSTKLAKSASKCKSQGASSSSSWQARSVADIKMSS 136

  Fly   123 SYNEEEATVTFNLDGKSV--RLGIDDALPLVEDEEFAALVARGCILNADAPPLEENAPWAR---- 181
            .||.........|..|.:  .:.:.|:.||...|         .::..|        ||.:
  Fly   137 IYNRSSTEAPAELYRKDLISAMKLPDSEPLANYE---------YLIVTD--------PWKQEWEK 184

  Fly   182 -VQVPV-------ARVAEIPDYRVSDAPPRPLAYYRFIEKSLEE---------------LDGEVE 223
             |||||       ..|..:|:..||.|....|...|::..:.:|               .:....
  Fly   185 GVQVPVNPDSLPEPCVYVLPEPVVSPAHDFKLPKNRYLRITKDEHYSPDLHYLTNVVALAENTCA 249

  Fly   224 YDVDEEDSAWLEHMNEERQRLGLNAVGIDTMELLMDRLEKESHFQAAA-----NGTPTGVEVDDD 283
            ||:|..|.|||...|.:|.:.|...:.....|.:::.||.....|...     .|  .|:|.|::
  Fly   250 YDIDPIDEAWLRLYNSDRAQCGAFPINATQFERVIEELEVRCWEQIQVILKLEEG--LGIEFDEN 312

  Fly   284 AVCCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQWLCRRCLQSPSKPVNCVLCPNAGG 348
            .:|.:|...:.:..|.::|||.||:.|||.|||:..||.||||||.|... .|| :||||||.||
  Fly   313 VICDVCRSPDSEEANEMVFCDNCNICVHQACYGITAIPSGQWLCRTCSMG-IKP-DCVLCPNKGG 375

  Fly   349 AFKQTDHGQ-WAHVVCALWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHR 412
            |.|....|: ||||.||||||||.......:|||..|.:||.:||.|.|.:|: |.:|:||||..
  Fly   376 AMKSNKSGKHWAHVSCALWIPEVSIGCVDRMEPITKISSIPQSRWSLICVLCR-KRVGSCIQCSV 439

  Fly   413 NSCYAAFHVTCAQQAGLYMTMDTVKDGHNDSSMHVQKFAYCHAHTPADAKLKMNVPDF------- 470
            ..|..|:|||||.|.||.|.. .:::|:.:..:.::  :||..|:.:..| |.|....
  Fly   440 KPCKTAYHVTCAFQHGLEMRA-IIEEGNAEDGVKLR--SYCQKHSMSKGK-KENAGSHGGGSASV 500

  Fly   471 -----------------------------EDTRHKMKEARKAL-AKKRSTAPVVLIPTIPPDRVQ 505
                                         ||.|.:....:..| :::|:.|..        .|:|
  Fly   501 ASAMQKANRYGSGAGGGADDGNNACGTTGEDPRRRKNHRKTELTSEERNQARA--------QRLQ 557

  Fly   506 EIATMVTMQRKKEF-----------------LDRIIA---YWTLK---RHYRNGVP-------LL 540
            |:        :.||                 .|.|:|   ||.||   ||.|..:|       ::
  Fly   558 EV--------EAEFDKHVNFNDISCHLFDVDDDAIVAIYNYWKLKRKSRHNRELIPPKSEDVEMI 614

  Fly   541 RRLQSQGN--NHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCELVRKREKLKVAFVR 603
            .|.|.|.:  ||.::..                     |||||||.|.||.:|.:||||..:..:
  Fly   615 ARKQEQQDMENHKLVVH---------------------LRQDLERVRNLCYMVSRREKLSRSLFK 658

  Fly   604 ISEEVVMLQLNPLEAALNKLLDALEARDSMQIFREPVDTSEVPDYTDIVKQPMDLGTMRAKLKEC 668
            :.|:|...||..|:..      .||.:.:.|..::||               |||
  Fly   659 LREQVFYKQLGVLDEM------RLEKQQTKQEQQQPV---------------MDL---------- 692

  Fly   669 QYNSLEQLEADFDLMIQNCLAY-NNKDTVFYRAGIRMRDQAAPLFVQVRKELQRDGLLARSQRYH 732
                             |.:.| |:..|::.|....:..|..|                  .:|
  Fly   693 -----------------NAVIYANDGPTLYDRFYSSVGGQTVP------------------AQY- 721

  Fly   733 VDHVEAEVEQELRLLLAAPASEGIVQKLLILADKSQVLKNPTYRTKKIKQIRLEISRMRKSLQKA 797
                     |:|:.:|     |.::.||                               :|.::.
  Fly   722 ---------QDLKYIL-----EQLMGKL-------------------------------QSGKQG 741

  Fly   798 RFAARHSSHANQSQSDDEDTLGGSPSKKRTRKRFNSSGVDMELGHDDDDEEEDSDEDSMGEDTVS 862
            |      ..|:||.:..:.....||:||.      ::|:             .|...|..|.||:
  Fly   742 R------GRASQSPNKRKQPAKASPNKKL------NNGI-------------LSSRTSSPEKTVA 781

  Fly   863 KDLLNSTQTPPCSPIKSLNNSSSPVGINRRTAILLTRKAQAALKRPSEPLTTPVKEEQHNSQSSN 927
            ...:.:|.:...||     ...:|.|  ||.:     |:.||                   .:::
  Fly   782 GSKVGTTTSKVRSP-----PGKNPTG--RRAS-----KSSAA-------------------AATS 815

  Fly   928 TQSTSGSSSSVTTAATAASSGAGTLNHVLSSAPPTASSFALTQNNSSGGGALASGTGIGGSSSAG 992
            |.:.|...|::.::.|:.|| :||:                    |||..:.|:||....|||..
  Fly   816 THNKSQFHSNIRSSTTSHSS-SGTI--------------------SSGNSSSANGTSSSDSSSGS 859

  Fly   993 TAAAASLTSTALAMNSKLSANLPVKSPKRPGRYRRVPEVRHSSSMSPKKSPNPAVTVSQALPMPE 1057
            .:.:.|.:|:|.:..||                      |.|||.||.|..:.|.:|.|.....:
  Fly   860 DSGSESGSSSAGSGVSK----------------------RKSSSGSPLKKQSYARSVEQRQKQRQ 902

  Fly  1058 TLPFERIPDSFRVYRANNQRDVSDSDD------------------APSQSSSPCSSCSDFSMSGS 1104
            ....|.:..:...|  .:.|..|.|.|                  .|.||.| ..:.|..|.|..
  Fly   903 RRQNEAVAGASATY--PDSRSASSSSDGEDERCRNRQEPERGARRGPIQSKS-VPNRSQASRSKP 964

  Fly  1105 CSDFDSDEASEGDA--------------DGDPDRDGGRSRSEE---------RDSTSQEGTTDAM 1146
            .::.|..|.:...|              |.|.|.......|||         |:||:..|.
  Fly   965 TTEADVGEGTGASARRKLSTTTRGLAQMDKDADESVSSDESEELLPLRGERQRESTTTSGL---- 1025

  Fly  1147 DMQHASLNNVQGNNGNMAISSSSGGSGGSSSEDDELE---ERPLSARQNK-------PMKVGTRG 1201
                |:..:..|.|....|.|.|..|.....:|.|.:   |..:|..||:       .||....|
  Fly  1026 ----ATTGSAIGRNLGQHIYSDSESSSSEQEKDQEEQATVESNVSDSQNQQTIRTKAAMKEFVPG 1086

  Fly  1202 TPTPTTMARAVALSAGRGRGKR--RSNLSESTSSTATPP--------------PLRRAGK----- 1245
            |...|:.....|.|..:.:..|  :...:...:||.|.|              |.|:|.|
  Fly  1087 TAATTSSTSQAASSTSKAKNTREGKEGAASIGNSTKTKPNPNAKLYPADLLVVPQRQAAKKASEN 1151

  Fly  1246 LRSAT------PNAS-----PLVNNIKARRNTTAAGSAPLTNNNRSKHSEDSASSERHNNHSHGQ 1299
            :||..      |:.|     |.:|:|.....:....|:...:|...|.|.:....:.|...:.|:
  Fly  1152 MRSTNLATTLQPDVSDRVREPDINSISGTAKSKVKDSSSRVSNEADKSSLEKVRPKEHLQKTVGK 1216

  Fly  1300 KPALEPLQLVWAKCRGYPWYPALILDPKTPK-----GFVYNGVP-LPA-----PPTDV---LALR 1350
            .....|.:      ||....|     ||.||     ....|..| ||.     ||:.|   ::.:
  Fly  1217 TSESAPAE------RGKRGRP-----PKVPKDARPPSITENDKPALPTHTQSKPPSVVATPVSAK 1270

  Fly  1351 KNCLDEIVFLVLFFD----VKRTWQWLPANK--LDILGIDKQLDQQKLVESR------------- 1396
            .|      |.|....    .|:..:.|.::|  |:.......:..::.|.|.
  Fly  1271 SN------FAVSLVPQRQAAKKAAEQLKSSKPVLESFSTGNDISDKETVTSATISGSGSSVPAAS 1329

  Fly  1397 ---KPAERKAVKKA 1407
               ||..|.::|:|
  Fly  1330 TPVKPTRRSSIKEA 1343

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_610266.1	SFP1	<22..61	CDD:227516	7/26 (27%)
		COG5141	203..>625	CDD:227470	151/511 (30%)
		Bromo_brd1_like	615..712	CDD:99944	16/97 (16%)
		MSCRAMM_ClfA	<1080..1163	CDD:468110	26/123 (21%)
		PWWP_BRPF	1303..1414	CDD:438964	29/141 (21%)
rno	NP_612007.2	COG5141	250..>664	CDD:227470	144/459 (31%)
		ePHD_RNO	367..480	CDD:277177	54/116 (47%)
		PHA03247	<1222..1481	CDD:223021	29/139 (21%)
		Chi1	2171..>2348	CDD:442692