Protein Alignment Br140 and jade3

DIOPT Version :10

• Sequence 1: NP_610266.1
• Gene: Br140 / 35648
• FlyBaseID: FBgn0033155
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: NP_970614.2
• Gene: jade3 / 322209
• ZFINID: ZDB-GENE-030131-928
• Length: 795
• Species: Danio rerio
• Alignment Length: 897
• Identity: 241/897 - (26%)
• Similarity: 371/897 - (41%)
• Gaps: 203/897 - (22%)

  Fly    94 RNGCSSASAGGGSAS-GVSARQY-ANPESLVSYNEEEATVTFNLDGKSVRLGIDDALPL-----V 151
            |...||.|:...|.| ..|:.:| :.|.:..|..::.|.|        .|..:..|:.|     :
Zfish     5 RTPSSSDSSDNESPSTSFSSNKYGSKPGTPASAQKKPAEV--------FRKDLISAMKLPDSHHI 61

  Fly   152 EDEEFAALVARGCILNADAPPLEENAPWAR-VQVPVARVAEI--PDYRVSDAPPRPLAY---YRF 210
            ..|::..|        ||....|    |.: ||| :|....|  |..|:....|:.:.:   .::
Zfish    62 SSEDYYLL--------ADTWKQE----WEKGVQV-LASPDTIPQPSVRIITEKPKEVLFSKPRKY 113

  Fly   211 IE-----------KSLEEL-DGEVEYDVDEEDSAWLEHMNEERQRLGLNAVGIDTMELLMDRLEK 263
            |:           .:::|| :....||:|:.|..||:.:|.|...:|...|...|||.:|:.||:
Zfish   114 IQCWSQDSTETGYVNIKELAEAMCRYDLDDMDLYWLQQLNAELGMMGDGVVDELTMERVMEALER 178

  Fly   264 ESH---FQAAANGTPTGVEVDDDAVCCICLDGECQNTNVILFCDMCNLAVHQDCYGVPYIPEGQW 325
            :.|   ..|.......|:|.|:|.:|.:|...:.:..|.::|||.||:.|||.|||:..:|:|.|
Zfish   179 QCHENMNHAIETEEGLGIEYDEDVICDVCRSPDSEEGNDMVFCDKCNICVHQACYGIVKVPDGNW 243

  Fly   326 LCRRCLQSPSKPVNCVLCPNAGGAFKQTDHG-QWAHVVCALWIPEVRFANTVFLEPIDSIETIPP 389
            |||.|:...:.  .|:|||..|||.|.|..| :||||.||||||||..|....:|||..:..|||
Zfish   244 LCRTCVLGITP--QCLLCPKTGGAMKATRAGTKWAHVSCALWIPEVSIACPERMEPITKVSHIPP 306

  Fly   390 ARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAGLYMTMDTVKDGHNDSSMHVQKFAYCH 454
            :||.|.|.:||.| .||||||...:|...||||||.:..|  .|.|:.|..::    |:..:||.
Zfish   307 SRWSLICSLCKLK-TGACIQCSVKNCTIPFHVTCAFEHSL--EMKTILDEGDE----VKFKSYCL 364

  Fly   455 AHTPADAKLKMNVPDFEDTRHKMKEARKAL---AKKRSTAPVVLIPTIPPDRVQEIATMVTMQRK 516
            .|    :|.|...|.....|||.......|   |:|...........:.|:.|..     .:...
Zfish   365 KH----SKPKAGEPGLSPARHKPPTETDKLSLRAQKLQELEEEFYTYVHPEEVAH-----DLSLP 420

  Fly   517 KEFLDRIIAYWTLKRHYRNGVPLLRRLQSQGNNHGVIQRNGIEGSPDTGELYRQLKYWQCLRQDL 581
            ...||.|..||.:||.......||...:.:.|.  ::|       |....::.:::.:..|||||
Zfish   421 LHLLDFIFQYWKMKRKSNFNKALLPPKEDEENL--LLQ-------PQEDSIHTRMRMFMHLRQDL 476

  Fly   582 ERARLLCELVRKREKLKVAFVRISEEVVMLQLNPLEAALNKLLDALEARDSMQIFREPVDTSEVP 646
            ||.|.||.:|.:|||||::..:..|::..|.:..:...|:..|....:.::: :|..|      |
Zfish   477 ERVRNLCYMVSRREKLKLSQSKAQEQIFNLHVKLVNQELSAGLPVSSSIENL-LFHPP------P 534

  Fly   647 DYTDIVKQP-MDLGTMRAKLKE-----CQYNSLEQLEADFDLMIQNCLAYNNKDTVFYRAGIRMR 705
            ..|..:|.| :.||..::..|.     |..||              |..|:..:     .||
Zfish   535 RITLKLKMPKVQLGNGKSSSKSGNGPLCPDNS--------------CNLYDTSE-----GGI--- 577

  Fly   706 DQAAPLFVQVRKELQR--DGLLARSQRYHVD-----------------HV-------------EA 738
            .|..|.....|:.::.  :|:|..|.....|                 |.             ||
Zfish   578 GQGKPQLHLGRQRIEERINGILPASIYIRRDGGTPPLAVKQSGKPLALHAALHGQSSNGKTKNEA 642

  Fly   739 EVEQELRLLLAAPASEGIVQKLLILADKSQVLKNPTYRTKKIKQIRLEISRMRKSLQKARFAARH 803
            |..::::       |.||:.|.::..|.|.:..:.       |..|.|||  .|| |.:.|....
Zfish   643 EKTRQIK-------SNGILDKPILQRDTSCLAASE-------KDPRSEIS--GKS-QPSGFHKTS 690

  Fly   804 SSHANQS---------QSDDEDTLGGSPSKKRTRKRFNSSGVDMEL----------------GHD 843
            ..|.::|         :::|..|.     :|.:||   |||....|                |:.
Zfish   691 LEHFSRSLKEATVSLVRTEDLRTF-----EKNSRK---SSGFSKPLSTERPQGGGRASQESDGYC 747

  Fly   844 DDDEEEDSDEDSMGEDTVSKDLLNSTQTPPCSPIKSLNNSSSPVGINRRTAI 895
            .|.|..||:.::.|:....    ..||......:||.:.:....|  .||::
Zfish   748 PDAELSDSEPEAKGKCRQG----GRTQNQRGDYVKSASRAKHSYG--SRTSV 793

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_610266.1	SFP1	<22..61	CDD:227516
		COG5141	203..>625	CDD:227470	145/443 (33%)
		Bromo_brd1_like	615..712	CDD:99944	20/102 (20%)
		MSCRAMM_ClfA	<1080..1163	CDD:468110
		PWWP_BRPF	1303..1414	CDD:438964
jade3	NP_970614.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..41		10/35 (29%)
		COG5141	139..555	CDD:227470	151/449 (34%)
		ePHD_JADE3	256..366	CDD:277176	56/116 (48%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	630..654		5/30 (17%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	667..687		8/29 (28%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	714..795		20/94 (21%)