Protein Alignment Br140 and Jade3

DIOPT Version :10

• Sequence 1: NP_610266.1
• Gene: Br140 / 35648
• FlyBaseID: FBgn0033155
• Length: 1430
• Species: Drosophila melanogaster
• Sequence 2: XP_038955504.1
• Gene: Jade3 / 299305
• RGDID: 1563945
• Length: 850
• Species: Rattus norvegicus
• Alignment Length: 1154
• Identity: 270/1154 - (23%)
• Similarity: 408/1154 - (35%)
• Gaps: 407/1154 - (35%)

  Fly    91 AEARNGCSSASAGGG-------------------------SASGVSARQYANPESLVSYNE---E 127
            :|:.:.|.|.|...|                         ||..:....:.||:|...:.:   |
  Rat    11 SESSDECPSTSFTSGSMYRKKSKNPKEHKKSAEVFRKDLISAMKIPDSHHINPDSYYLFTDTWKE 75

  Fly   128 EATVTFNLDGKSVRLGID-DALPLVEDEEFAALVARGCILNADAPPLEENAPWARVQVPVARVAE 191
            |..       |.|::..: |::|.      .:|.:|...|.....|...:.|          |.:
  Rat    76 EWE-------KGVQVPANPDSVPT------PSLRSRNRTLPTPQKPFFCSLP----------VTD 117

  Fly   192 IPDYRVSDAP------PRPLAYYR----------FIEKSLEELDGEVEYDVDEEDSAWLEHMNEE 240
            :|..|:....      .||..|.|          :| .:||.......||:|:.|..||:.:||:
  Rat   118 LPHRRIISEKVKEILFVRPRKYIRCSSPESAEPGYI-NTLELAASTCRYDLDDMDIFWLQELNED 181

  Fly   241 RQRLGLNAVGIDTMELLMDRLEKESH---FQAAANGTPTGVEVDDDAVCCICLDGECQNTNVILF 302
            ...:|...:....||..::.||:..|   ..|.......|:|.|:|.:|.:|...:.:..|.::|
  Rat   182 LGEMGYGPIDETLMEKTIEVLERHCHENMNHAIETVEGLGIEYDEDVICDVCRSPDSEEGNDMVF 246

  Fly   303 CDMCNLAVHQDCYGVPYIPEGQWLCRRCLQS--PSKPVNCVLCPNAGGAFKQTDHG-QWAHVVCA 364
            ||.||:.|||.|||:..||||.||||.|:..  |    .|||||..|||.|.|..| :||||.||
  Rat   247 CDKCNVCVHQACYGILKIPEGSWLCRSCVLGIYP----QCVLCPKKGGAMKTTRTGTKWAHVSCA 307

  Fly   365 LWIPEVRFANTVFLEPIDSIETIPPARWRLTCYVCKEKGLGACIQCHRNSCYAAFHVTCAQQAGL 429
            ||||||..|....:||:..|..|||:||.|.|.:||.| .||||||...||..|||||||.:.||
  Rat   308 LWIPEVSIACPERMEPVTKISHIPPSRWALVCNLCKLK-TGACIQCSVKSCITAFHVTCAFEHGL 371

  Fly   430 YMTMDTVKDGHNDSSMHVQKFAYCHAHTPADAKLKMNVPDFEDTRHKMKEARKALAKKRSTAPVV 494
              .|.|:.|..::    |:..::|..|:....||    .|.|...|:..|..:|.::|.|.....
  Rat   372 --EMKTILDEGDE----VKFKSFCLKHSQNKPKL----GDAEYHHHRAAEQSQAKSEKTSLRAQK 426

  Fly   495 LIPTIPPDRVQEIATMVTMQR-KKEF------LDRIIAYWTLKRHYRNGVPLLRRLQSQGNNHGV 552
            |     .:..:|..|:|.::. .||.      :|.|..||.|||......||:...:.:.|  |:
  Rat   427 L-----RELEEEFYTLVQVEDVAKEMGLSAFTVDFIYNYWKLKRKSNFNKPLIPPKEDEQN--GL 484

  Fly   553 IQRNGIEGSPDTGELYRQLKYWQCLRQDLERARLLCELVRKREKLKVAFVRISEEVVMLQLNPLE 617
            :|       |....::.:::.:..|||||||.|.||.::.:|||||::..::.|::..||
  Rat   485 VQ-------PKEESIHTRMRMFMHLRQDLERVRNLCYMISRREKLKLSHTKVQEQIFGLQ----- 537

  Fly   618 AALNKLLDALEARDSMQIFREPVDTSEVPDYTDIVKQPMDLGTMRAKLKECQYNSLEQLEADFDL 682
                           :|:..|.:        ||                              .|
  Rat   538 ---------------VQLINEEI--------TD------------------------------GL 549

  Fly   683 MIQNCLAYNNKDTVFYRAGIRMRDQAAPLFVQVRKELQRDGLLARSQRYHVDHVEAEVEQELRLL 747
            .:.|.|    ::::||
  Rat   550 SLTNAL----ENSLFY------------------------------------------------- 561

  Fly   748 LAAPASEGIVQKLLILADKSQVLKNPTYRTKKIKQIRLEISRMRKSLQKARFAARHSSHANQSQS 812
                                    .|...|.|:|        |.||
  Rat   562 ------------------------PPPRITLKLK--------MPKS------------------- 575

  Fly   813 DDEDTLGGSPSKKRTRKRFNSSGVDMELGHDDDDEEEDSDEDSMGEDTVSKDLLNSTQTPPCSPI 877
                                                  :.||       .:|....|:..|.||
  Rat   576 --------------------------------------TSED-------CRDSSTETEHQPSSP- 594

  Fly   878 KSLNNSSSPVGINRRTAILLTRKAQAALKRPSEPLTTPVK-------EEQHN---SQSSNTQSTS 932
                .||||            ..::.:.:.|.|||...||       |.:.|   :..|::||.:
  Rat   595 ----GSSSP------------SHSKRSPEMPEEPLDMNVKIYPRYPLESKSNCVLASRSHSQSET 643

  Fly   933 GSSSSVTTAATAASSGAGTLNHVLSSAPPTASSFALTQNNSSGGG------ALASGTGIGGSSSA 991
            .|||....|.:|......||      ..|.|...||....|.|.|      .|||..|:.|:.|.
  Rat   644 RSSSPTQRAPSAEFYHGQTL------GKPLALQAALHGQASIGNGKNQPNSRLASSNGLEGNWSG 702

  Fly   992 GTAAAASLTSTALAMNSKLSANLPVKSPKRPGRYRRVPEVRHSS----SMSPKKSPNPAVTVSQA 1052
            ......:.........|.||::||...           .:|.|.    |.|.|::.|..|..::.
  Rat   703 NITQKVNSGEMCYDQESMLSSHLPSSG-----------NIRKSGMEHFSRSFKEATNTWVKPNED 756

  Fly  1053 L-----PMPETLPFERIPDSFRVYRANNQRDVSDSDDAPSQSSSPCSSCSDFSMSGSCSDFDSDE 1112
            |     |.......|::.....:.|:..:....::|                   |.|.|.   |
  Rat   757 LQYCVKPTKNVSSKEQLWGRPLLRRSTGRASYQETD-------------------GYCPDL---E 799

  Fly  1113 ASEGDADGDPDRDGGRSR--SEERDSTSQE------GTTDAMDMQHASL 1153
            .|:.:|:|:.:::..|.:  |.:|::.|.:      |.|......|:|:
  Rat   800 PSDSEAEGEGNKETVRVKRESSDRENPSHDSARECHGKTKTHPHSHSSM 848

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Br140	NP_610266.1	SFP1	<22..61	CDD:227516
		COG5141	203..>625	CDD:227470	156/444 (35%)
		Bromo_brd1_like	615..712	CDD:99944	9/96 (9%)
		MSCRAMM_ClfA	<1080..1163	CDD:468110	16/82 (20%)
		PWWP_BRPF	1303..1414	CDD:438964
Jade3	XP_038955504.1	EPL1	<74..204	CDD:463128	33/153 (22%)
		COG5141	165..>536	CDD:227470	147/399 (37%)
		PHD_SF	282..392	CDD:473978	59/116 (51%)