Protein Alignment Tsp42Ef and CD53

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_000551.1
• Gene: CD53 / 963
• HGNCID: 1686
• Length: 219
• Species: Homo sapiens
• Alignment Length: 220
• Identity: 50/220 - (22%)
• Similarity: 101/220 - (45%)
• Gaps: 30/220 - (13%)

  Fly     5 SSVKLIVYAL---DVLCTLLALVLISFGIYVAVSYN----LNEIGQLTAYG-YVGLGAAALLVVL 61
            ||:||:.|.|   ::|..:....::.||||:.:..|    .:.:..||... :|.:|:..::|..
Human     4 SSLKLLKYVLFFFNLLFWICGCCILGFGIYLLIHNNFGVLFHNLPSLTLGNVFVIVGSIIMVVAF 68

  Fly    62 WGYLSAWRENVCCTVTFIIFLCLVIIAQFAVVYLLITQEKT----VASNLANALEATWEEELNSP 122
            .|.:.:.:||.|..::|.|.|.::::|:..:..||...|:.    ||..|.:::. .:..:.::.
Human    69 LGCMGSIKENKCLLMSFFILLLIILLAEVTLAILLFVYEQKLNEYVAKGLTDSIH-RYHSDNSTK 132

  Fly   123 GAMSLYQNWFQCCGRGSPQDYIVNERLPPETCFRNHDKSKPENLIHTGCRVEFENYWQHLTKIF- 186
            .|....|::.||||.....|:...   ||.:|        |.:....||..: ...|.|...::
Human   133 AAWDSIQSFLQCCGINGTSDWTSG---PPASC--------PSDRKVEGCYAK-ARLWFHSNFLYI 185

  Fly   187 NILALVLIGFELL----LSVISCRL 207
            .|:.:.:...|:|    ...::|::
Human   186 GIITICVCVIEVLGMSFALTLNCQI 210

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	48/218 (22%)
CD53	NP_000551.1	Tetraspanin	9..208	CDD:459767	45/211 (21%)
		CD53_like_LEL	104..186	CDD:239417	19/94 (20%)