Protein Alignment Tsp42Ef and CD37

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: XP_005259492.1
• Gene: CD37 / 951
• HGNCID: 1666
• Length: 365
• Species: Homo sapiens
• Alignment Length: 266
• Identity: 52/266 - (19%)
• Similarity: 102/266 - (38%)
• Gaps: 71/266 - (26%)

  Fly     5 SSVKLIVYALDVLCTLLALVLISFGIYVAVSYNLNEIGQLTAYGYVGL---------------GA 54
            |.:|..::..::...:|..::..|||::.       |.:.:...:|||               |.
Human     9 SLIKYFLFVFNLFFFVLGSLIFCFGIWIL-------IDKTSFVSFVGLAFVPLQIWSKVLAISGI 66

  Fly    55 AALLVVLWGYLSAWRENVCCTVTFIIFLCLVIIAQFAVVYLLITQEKTVASNLANALEATWEEEL 119
            ..:.:.|.|.:.|.:|..|....:...|.|:...|..:..|:.||...:..:|.:.:|.|.::..
Human    67 FTMGIALLGCVGALKELRCLLGLYFGMLLLLFATQITLGILISTQRAQLERSLRDVVEKTIQKYG 131

  Fly   120 NSPGAMSLYQNW----FQ--CCGRGSPQDYI---------VNERLPPETCFR---NHDKSKPENL 166
            .:|...:..::|    ||  |||...|||:.         ......|.:|:.   .:|.:..:.:
Human   132 TNPEETAAEESWDYVQFQLRCCGWHYPQDWFQVLILRGNGSEAHRVPCSCYNLSATNDSTILDKV 196

  Fly   167 I--------------HTG--CRVEFENY------------WQHLTKIFNILALVL-IG-FELLLS 201
            |              |:.  |.|..|::            |.| ..:.:|:.:.| :| .|:.:.
Human   197 ILPQLSRLGHLARSRHSADICAVPAESHIYREGCAQGLQKWLH-NNLISIVGICLGVGLLEMTVM 260

  Fly   202 VISCRL 207
            |:|.:|
Human   261 VLSVQL 266

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	51/264 (19%)
CD37	XP_005259492.1	Tetraspanin	26..266	CDD:459767	48/247 (19%)
		CD37_CD82_like_LEL	108..243	CDD:239413	25/135 (19%)