DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Tsp42Ef and TSPAN18

DIOPT Version :10

Sequence 1:NP_523632.2 Gene:Tsp42Ef / 35615 FlyBaseID:FBgn0033127 Length:220 Species:Drosophila melanogaster
Sequence 2:XP_005253274.1 Gene:TSPAN18 / 90139 HGNCID:20660 Length:258 Species:Homo sapiens


Alignment Length:252 Identity:51/252 - (20%)
Similarity:92/252 - (36%) Gaps:54/252 - (21%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 SSVKLIVYALDVLCTLLALVLISFGIYVAVS-------YNLNEIGQLTAYGYVGLGAAALLVVLW 62
            |.:|.:::..:....|....|::.||:|.|.       ...|.:....||..:.:|....|:...
Human    17 SCMKYLMFVFNFFIFLGGACLLAIGIWVMVDPTGFREIVAANPLLLTGAYILLAMGGLLFLLGFL 81

  Fly    63 GYLSAWRENVCCTVTFIIFLCLVIIAQFAVVYL-----------LITQEKT---VASNLANALEA 113
            |...|.|||.|..:.|.:|:.::.:|:.:...|           ..|:|.|   ..:|..:...|
Human    82 GCCGAVRENKCLLLFFFLFILIIFLAELSAAILAFIFRENLTREFFTKELTKHYQGNNDTDVFSA 146

  Fly   114 TWEEELNSPGAMSLYQNWFQCCGRGSPQDY---------IVNERLPPETCFRNHDKSKPENLI-- 167
            ||...:.:          |.|||...|:|:         .::....||.|.|...:|:...|:  
Human   147 TWNSVMIT----------FGCCGVNGPEDFKFASVFRLLTLDSEEVPEACCRREPQSRDGVLLSR 201

  Fly   168 ------------HTGCRVEFENYWQHLTKIFNILALVLIGFELLLSVISCRLCNSIR 212
                        ..||.....|.::....:...||:.::..||...:.:..|...|:
Human   202 EECLLGRSLFLNKQGCYTVILNTFETYVYLAGALAIGVLAIELFAMIFAMCLFRGIQ 258

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EfNP_523632.2 Tetraspanin 7..209 CDD:459767 49/245 (20%)
TSPAN18XP_005253274.1 Tetraspanin 20..255 CDD:459767 49/244 (20%)
uroplakin_I_like_LEL 115..228 CDD:239409 22/122 (18%)

Return to query results.
Submit another query.