Protein Alignment Tsp42Ef and TSPAN6

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_003261.1
• Gene: TSPAN6 / 7105
• HGNCID: 11858
• Length: 245
• Species: Homo sapiens
• Alignment Length: 234
• Identity: 49/234 - (20%)
• Similarity: 100/234 - (42%)
• Gaps: 42/234 - (17%)

  Fly     9 LIVYALDVLCTLLALVLISFGIYVAVSYN-----LNEIGQLTAYGYVGLGAAALLVVLWGYLSAW 68
            |::|..  :..:..::|::.||:..||..     |||......:..:..|...:|:..:|..:..
Human    21 LLIYTF--IFWITGVILLAVGIWGKVSLENYFSLLNEKATNVPFVLIATGTVIILLGTFGCFATC 83

  Fly    69 RENVCCTVTFIIFLCLVIIAQF--AVVYLLITQEKTVASNLANALEATWEEEL---NSPG----- 123
            |.:......:.:||.||.:.:.  |:|..:...|      :.|:.:..:|:.|   ||.|
Human    84 RASAWMLKLYAMFLTLVFLVELVAAIVGFVFRHE------IKNSFKNNYEKALKQYNSTGDYRSH 142

  Fly   124 AMSLYQNWFQCCGRGSPQDY----IVNERLPPETCFRNHD---KSKPENLIHTGCRVEFENYWQH 181
            |:...||...|||....:|:    ..:|:..|::|.:..|   :...:.:.:.||.::.
Human   143 AVDKIQNTLHCCGVTDYRDWTDTNYYSEKGFPKSCCKLEDCTPQRDADKVNNEGCFIKV------ 201

  Fly   182 LTKI---FNILALVLIG---FELLLSVISCRLCNSIRND 214
            :|.|   ..::|.:..|   |:|:...::..|..:|.|:
Human   202 MTIIESEMGVVAGISFGVACFQLIGIFLAYCLSRAITNN 240

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	47/227 (21%)
TSPAN6	NP_003261.1	Tetraspanin	17..235	CDD:459767	47/227 (21%)
		TM4SF2_6_like_LEL	112..209	CDD:239414	22/108 (20%)