Protein Alignment Tsp42Ef and Tspan14

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_666040.1
• Gene: Tspan14 / 52588
• MGIID: 1196325
• Length: 270
• Species: Mus musculus
• Alignment Length: 235
• Identity: 45/235 - (19%)
• Similarity: 90/235 - (38%)
• Gaps: 47/235 - (20%)

  Fly     8 KLIVYALDVLCTLLALVLISFGIYV----AVSYNLNEIGQLTAYGYVGL----GAAALLVVLWGY 64
            |.::::.:::..|..:|.:..|::.    .|..:|.::.:|.....|.|    |.....:...|.
Mouse    16 KYLLFSYNIVFWLAGVVFLGVGLWAWSEKGVLSDLTKVTRLHGIDPVVLVLMVGVVMFTLGFAGC 80

  Fly    65 LSAWRENVCCTVTFIIFLCLVIIAQFAVVYLLITQEKTVASNLANALEA---TWEEELNSPGAMS 126
            :.|.|||:|....|...:.|:...:.||..|....:..|........|:   ::.::::....:.
Mouse    81 VGALRENICLLKFFCGAIVLIFFLELAVAVLAFLFQDWVRDRFREFFESNIKSYRDDIDLQNLID 145

  Fly   127 LYQNWFQCCGRGSPQDYIVN------------ER--LPPETCFRNHDKSKPENLIHTGC----RV 173
            ..|...||||...|:|:.:|            |:  :|...|.    ....:.:::|.|    |:
Mouse   146 SLQKANQCCGAYGPEDWDLNVYFNCSGASYSREKCGVPFSCCV----PDPAQKVVNTQCGYDVRI 206

  Fly   174 EFENYWQH--------------LTKIFNILALVLIGFELL 199
            :.::.|..              |.:...|:|.|.|...||
Mouse   207 QLKSKWDEFIFTKGCIQALEGWLPRNIYIVAGVFIAISLL 246

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	45/235 (19%)
Tspan14	NP_666040.1	Tetraspanin	16..258	CDD:459767	45/235 (19%)
		TM4SF9_like_LEL	113..233	CDD:239412	18/123 (15%)
		Necessary and sufficient for interaction with ADAM10. /evidence=ECO:0000250|UniProtKB:Q8NG11	114..232		18/121 (15%)