Protein Alignment Tsp42Ef and TSPAN33

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_848657.1
• Gene: TSPAN33 / 340348
• HGNCID: 28743
• Length: 283
• Species: Homo sapiens
• Alignment Length: 259
• Identity: 56/259 - (21%)
• Similarity: 108/259 - (41%)
• Gaps: 60/259 - (23%)

  Fly     7 VKLIVYALDVLCTLLALVLISFGIYVAVSYNLNEIGQLTAYGYVGLGAAALLVVL---------W 62
            ||.:::..::|..::::|:::.|:|..:..:..     .|...:.:..|.||:|:         .
Human    22 VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAE-----AALACLAVDPAILLIVVGVLMFLLTFC 81

  Fly    63 GYLSAWRENVCCTVTFIIFLCLVIIAQFA---VVYLLITQEKTVASNLANALEATWEEELNSPGA 124
            |.:.:.|||:|...||.:.|..|.:.|.|   :.::...:.:...|.:.|.....:.::|:....
Human    82 GCIGSLRENICLLQTFSLCLTAVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDLDLQNL 146

  Fly   125 MSLYQNWFQCCGRGSPQDYIVN------------ER--LPPETCFRNHDKS-------------- 161
            :...|..|.|||..|.:|:..|            ||  :|...|....|::
Human   147 IDFGQKKFSCCGGISYKDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPDQAVINTMCGQGMQAFD 211

  Fly   162 --KPENLIHT-GCRVEFENYWQHLTKIFNILALVLIGFE------LLLSVISCRLCNSIRNDAR 216
              :...:|:| ||..:..| |.| :.:| :|..|.:|..      :|||.|   |.|.|::..:
Human   212 YLEASKVIYTNGCIDKLVN-WIH-SNLF-LLGGVALGLAIPQLVGILLSQI---LVNQIKDQIK 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	54/250 (22%)
TSPAN33	NP_848657.1	Tetraspanin	22..262	CDD:459767	54/250 (22%)
		penumbra_like_LEL	116..236	CDD:239411	23/121 (19%)