DRSC/TRiP Functional Genomics Resources

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Protein Alignment Tsp42Ef and Tspan18

DIOPT Version :10

Sequence 1:NP_523632.2 Gene:Tsp42Ef / 35615 FlyBaseID:FBgn0033127 Length:220 Species:Drosophila melanogaster
Sequence 2:NP_001101220.1 Gene:Tspan18 / 311210 RGDID:1560411 Length:248 Species:Rattus norvegicus


Alignment Length:253 Identity:54/253 - (21%)
Similarity:93/253 - (36%) Gaps:56/253 - (22%)


- Green bases have known domain annotations that are detailed below.


  Fly     5 SSVKLIVYALDVLCTLLALVLISFGIYVAVS-YNLNEI----GQLTAYGYVGLGAAALLVVLWGY 64
            |.:|.:::..:....|....|:..||:|.|. ....||    ..||...||.|....||.:| |:
  Rat     7 SCMKYLMFVFNFFVFLGGACLLGVGIWVLVDPTGFREIVATNPLLTTGAYVVLAMGGLLFLL-GF 70

  Fly    65 L---SAWRENVCCTVTFIIFLCLVIIAQFAVVYL-----------LITQEKT---VASNLANALE 112
            |   .|.|||.|..:.|.:|:.::.:.:.:...|           ..|:|.|   ...|..:...
  Rat    71 LGCCGAVRENRCLLLFFFLFILIIFLVELSAAILAFIFREHLTREFFTKELTKHYQGDNDTDVFS 135

  Fly   113 ATWEEELNSPGAMSLYQNWFQCCGRGSPQDY---------IVNERLPPETCFRNHDKSKPENLI- 167
            |||...:.:          |.|||...|:|:         .::....|:.|.|...:::...:: 
  Rat   136 ATWNSVMIT----------FGCCGVNGPEDFKLASVFRLLTLDTEEVPKACCRREPQTRDGVVLS 190

  Fly   168 -------------HTGCRVEFENYWQHLTKIFNILALVLIGFELLLSVISCRLCNSIR 212
                         ..||.....|.::....:....|:.::..||.|.|.:..|...|:
  Rat   191 REECQLGRNPFINKQGCYTVILNTFETYVYLAGAFAIGVLAIELFLMVFAMCLFRGIQ 248

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Tsp42EfNP_523632.2 Tetraspanin 7..209 CDD:459767 52/246 (21%)
Tspan18NP_001101220.1 Tetraspanin 10..245 CDD:459767 52/245 (21%)
uroplakin_I_like_LEL 105..218 CDD:239409 19/122 (16%)

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