Protein Alignment Tsp42Ef and Tspan12

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_766595.1
• Gene: Tspan12 / 269831
• MGIID: 1889818
• Length: 305
• Species: Mus musculus
• Alignment Length: 245
• Identity: 54/245 - (22%)
• Similarity: 104/245 - (42%)
• Gaps: 48/245 - (19%)

  Fly     1 MASTSSVK---LIVYALDVLCTLLALVLISFGIYVAVSYNLNEIGQLTAYGYVGLGAAALLVVLW 62
            ||...|||   .::|||::|..|:::.:::...::. .| ||.:..|||...|   ..|:::..:
Mouse     1 MAREDSVKCLRCLLYALNLLFWLMSISVLAVSAWMR-DY-LNNVLTLTAETRV---EEAVILTYF 60

  Fly    63 GYLSAWRENVCCTVTFIIFL--C------LVIIAQFAVVYLLI----------TQEKTVASNLAN 109
            ..:......|||.:..:..|  |      |:::|.:....|:|          |.|:.|...:..
Mouse    61 PVVHPVMIAVCCFLIIVGMLGYCGTVKRNLLLLAWYFGTLLVIFCVELACGVWTYEQEVMVPVQW 125

  Fly   110 ALEATWEEELNSPG---------AMSLYQNWFQCCGRGSPQDYIVNERL--PPETC----FRNHD 159
            :...|.:..:.:.|         |.:.:|..|:|||.....|::....:  ||::|    |....
Mouse   126 SDMVTLKARMTNYGLPRYRWLTHAWNYFQREFKCCGVVYFTDWLEMTEMDWPPDSCCVREFPGCS 190

  Fly   160 KSKPE----NLIHTGCRVEFENYWQHLTKIFNILAL--VLIGFELLLSVI 203
            |...:    :|...||..:..::.:. ||...:|..  :.||...:|::|
Mouse   191 KQAHQEDLSDLYQEGCGKKMYSFLRG-TKQLQVLRFLGISIGVTQILAMI 239

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	51/239 (21%)
Tspan12	NP_766595.1	Tetraspanin	10..246	CDD:459767	49/236 (21%)
		TM4SF12_like_LEL	116..218	CDD:239410	19/102 (19%)