Protein Alignment Tsp42Ef and TSPAN17

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_001353420.1
• Gene: TSPAN17 / 26262
• HGNCID: 13594
• Length: 355
• Species: Homo sapiens
• Alignment Length: 239
• Identity: 54/239 - (22%)
• Similarity: 97/239 - (40%)
• Gaps: 55/239 - (23%)

  Fly     8 KLIVYALDVLCTLLALVLISFGIYV-AVSYNLNEIGQLTAYGYVGLGAAALLVVLWGYLS----- 66
            |..::..:::..:|..:.::.|::. .....|:.|..||..|  ||....|.||:.|.:|
Human    18 KYFLFGFNIVFWVLGALFLAIGLWAWGEKGVLSNISALTDLG--GLDPVWLFVVVGGVMSVLGFA 80

  Fly    67 ----AWRENVCCTVTFIIFLCLVIIAQFAVVYLLITQEKTVASNL----ANALEATWEEELNSPG 123
                |.|||......|.:||.|:...:.|...|....:..:...|    .|.::| :.::::...
Human    81 GCIGALRENTFLLKFFSVFLGLIFFLELATGILAFVFKDWIRDQLNLFINNNVKA-YRDDIDLQN 144

  Fly   124 AMSLYQNWFQCCGRGSPQDYIVN------------ER--LPPETCFRN-----------HD---- 159
            .:...|.::.|||...|.|:.:|            ||  :|...|.|:           :|
Human   145 LIDFAQEYWSCCGARGPNDWNLNIYFNCTDLNPSRERCGVPFSCCVRDPAEDVLNTQCGYDVRLK 209

  Fly   160 -KSKPENLIHT-GCRVEFENYWQHLTKIFNILAL--VLIGFELL 199
             :.:.:..||| ||..:||.:.|.     |::.:  |.:|..||
Human   210 LELEQQGFIHTKGCVGQFEKWLQD-----NLIVVAGVFMGIALL 248

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	54/239 (23%)
TSPAN17	NP_001353420.1	Tetraspanin	18..>157	CDD:459767	30/141 (21%)
		TM4SF9_like_LEL	115..235	CDD:239412	24/125 (19%)