Protein Alignment Tsp42Ef and Tspan33

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_666285.1
• Gene: Tspan33 / 232670
• MGIID: 1919012
• Length: 283
• Species: Mus musculus
• Alignment Length: 256
• Identity: 53/256 - (20%)
• Similarity: 110/256 - (42%)
• Gaps: 54/256 - (21%)

  Fly     7 VKLIVYALDVLCTLLALVLISFGIYVAVSYNLNEIGQLTAYGYVGLGAAALLVVL---------W 62
            ||.:::..::|..::::|:::.|:|..:..:..     .|...:.:..|.||:|:         .
Mouse    22 VKYLLFFFNMLFWVISMVMVAVGVYARLMKHAE-----AALACLAVDPAILLIVVGVLMFLLTFC 81

  Fly    63 GYLSAWRENVCCTVTFIIFLCLVIIAQFA---VVYLLITQEKTVASNLANALEATWEEELNSPGA 124
            |.:.:.|||:|...||.:.|.:|.:.|.|   :.::...:.:...|.:.|.....:.::|:....
Mouse    82 GCIGSLRENICLLQTFSLCLTIVFLLQLAAGILGFVFSDKARGKVSEIINNAIVHYRDDLDLQNL 146

  Fly   125 MSLYQNWFQCCGRGSPQDYIVN------------ER--LPPETCFRNHDKS-------------- 161
            :...|..|.|||..|.:|:..|            ||  :|...|....:::
Mouse   147 IDFGQKKFSCCGGISYRDWSQNMYFNCSEDNPSRERCSVPYSCCLPTPNQAVINTMCGQGMQALD 211

  Fly   162 --KPENLIHT-GCRVEFENYWQHLTKIFNILALVLIGF---ELLLSVISCRLCNSIRNDAR 216
              :...:|:| ||..:..| |.| :.:| :|..|.:|.   :|:..::|..|.|.|::..:
Mouse   212 YLEASKVIYTNGCIDKLVN-WIH-SNLF-LLGGVALGLAIPQLVGILLSQVLVNQIKDQIK 269

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	51/247 (21%)
Tspan33	NP_666285.1	Tetraspanin	22..262	CDD:459767	51/247 (21%)
		penumbra_like_LEL	116..236	CDD:239411	22/121 (18%)