Protein Alignment Tsp42Ef and Cd63

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_031679.1
• Gene: Cd63 / 12512
• MGIID: 99529
• Length: 238
• Species: Mus musculus
• Alignment Length: 240
• Identity: 68/240 - (28%)
• Similarity: 103/240 - (42%)
• Gaps: 49/240 - (20%)

  Fly     7 VKLIVYALDVLCTLLALVLISFGIYV------AVSYNLNEIGQLTAYGYVGLGAAALLVVLWGYL 65
            ||.::|.|.:.....|:.||:.|:.|      |:::. ...|.|.....:.:||...||...|..
Mouse    10 VKFLLYVLLLAFCACAVGLIAIGVAVQVVLKQAITHE-TTAGSLLPVVIIAVGAFLFLVAFVGCC 73

  Fly    66 SAWRENVCCTVTFIIFLCLVIIAQFAVV---YLLITQ-----EKTVASNLANALE----ATWEEE 118
            .|.:||.|..:||.|||.|:::.:.||.   |:...|     .|:....:.|.|:    ||..::
Mouse    74 GACKENYCLMITFAIFLSLIMLVEVAVAIAGYVFRDQVKSEFNKSFQQQMQNYLKDNKTATILDK 138

  Fly   119 LNSPGAMSLYQNWFQCCGRGSPQDY-----IVNERLPPETCFR------NHDKSKPENLIHT-GC 171
            |         |....|||..:..|:     :..:|:|...|..      |..|   |:.||| ||
Mouse   139 L---------QKENNCCGASNYTDWENIPGMAKDRVPDSCCINITVGCGNDFK---ESTIHTQGC 191

  Fly   172 RVEFENYWQHLTKIFNILALVLIGF---ELLLSVISCRLCNSIRN 213
             ||....|  |.|...::|...:|.   |:|..:.||.|..|||:
Mouse   192 -VETIAIW--LRKNILLVAAAALGIAFVEVLGIIFSCCLVKSIRS 233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	65/234 (28%)
Cd63	NP_031679.1	Tetraspanin	10..229	CDD:459767	65/234 (28%)
		CD63_LEL	105..203	CDD:239419	29/112 (26%)
		Lysosomal targeting motif. /evidence=ECO:0000269|PubMed:21041449	234..238		68/240 (28%)