Protein Alignment Tsp42Ef and TSPAN3

DIOPT Version :10

• Sequence 1: NP_523632.2
• Gene: Tsp42Ef / 35615
• FlyBaseID: FBgn0033127
• Length: 220
• Species: Drosophila melanogaster
• Sequence 2: NP_005715.1
• Gene: TSPAN3 / 10099
• HGNCID: 17752
• Length: 253
• Species: Homo sapiens
• Alignment Length: 241
• Identity: 57/241 - (23%)
• Similarity: 93/241 - (38%)
• Gaps: 34/241 - (14%)

  Fly     4 TSSVKLIVY-------ALDVLCTLLALVLISFGIY---VAVSYNLNEIGQLTAYGYVGLGAAALL 58
            |||..::|:       |..:||.:.|.|.|::..|   ....|.|     :.|...:.:||...:
Human     7 TSSKTVLVFLNLIFWGAAGILCYVGAYVFITYDDYDHFFEDVYTL-----IPAVVIIAVGALLFI 66

  Fly    59 VVLWGYLSAWRENVCCTVTFIIFLCLVIIAQFAVVYLLITQEKTVASNLANALEATWEE-ELNSP 122
            :.|.|..:..||:.|...||:|.|.||.:.:..||.|.......|.:.:..:::..::. ...:|
Human    67 IGLIGCCATIRESRCGLATFVIILLLVFVTEVVVVVLGYVYRAKVENEVDRSIQKVYKTYNGTNP 131

  Fly   123 GAMS----LYQNWFQCCGRGSPQDY--------IVNERLPPETCFR-----NHDKSKPENLIHTG 170
            .|.|    ..|....|||..:..|:        ..|:.:|...|..     |...:.|.:|...|
Human   132 DAASRAIDYVQRQLHCCGIHNYSDWENTDWFKETKNQSVPLSCCRETASNCNGSLAHPSDLYAEG 196

  Fly   171 CRVEFENYWQHLTKIFNILALVLIGFELLLSVISC-RLCNSIRNDA 215
            |........|.:.......||.....:||..:.:| .||...|:.|
Human   197 CEALVVKKLQEIMMHVIWAALAFAAIQLLGMLCACIVLCRRSRDPA 242

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsp42Ef	NP_523632.2	Tetraspanin	7..209	CDD:459767	51/230 (22%)
TSPAN3	NP_005715.1	Tetraspanin	9..235	CDD:459767	51/230 (22%)
		TM4SF8_like_LEL	104..210	CDD:239416	18/105 (17%)