DRSC/TRiP Functional Genomics Resources

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Protein Alignment vimar and Rap1gds1

DIOPT Version :10

Sequence 1:NP_995767.1 Gene:vimar / 35609 FlyBaseID:FBgn0022960 Length:635 Species:Drosophila melanogaster
Sequence 2:NP_001401991.1 Gene:Rap1gds1 / 310909 RGDID:1308558 Length:607 Species:Rattus norvegicus


Alignment Length:634 Identity:193/634 - (30%)
Similarity:320/634 - (50%) Gaps:77/634 - (12%)


- Green bases have known domain annotations that are detailed below.


  Fly     6 IDDLIEKLKTTSVSPANTT--------NLLCEISATKDPKLFDKHE---LAECFLGLTKCDDTNV 59
            :|:|.:.||...::.|:.|        :.|.:..|..:.:..:|.:   :.:.|..|. ....:.
  Rat     1 MDNLSDALKKLKITAADKTEGSLEGCLDCLLQALAQNNAETSEKIQGSGILQLFANLL-TPQASC 64

  Fly    60 RKEAAKCIAEITKSEVQRKKFTKRNIIAAFLECLRQVPTSDGSMELPIQICRALGNICYLNDEAR 124
            ..:.|..|||:.|:|..|.......:|:..::.|     :....|:.:|..||||||||.:.|.|
  Rat    65 TAKVANIIAEVAKNEFMRIPCVDAGLISPLVQLL-----NSKDQEVLLQTGRALGNICYDSHEGR 124

  Fly   125 DLILELEGDAVLL-RLLDITTIEDVANAAQFIKVRGGLLSNYLLGGEGLAKRAMELGVMKKLQGI 188
            ..:.:..|..::: .|..:....|.|| .:.:.|..|:|.||....:.|..:.:.:||:..|..:
  Rat   125 SAVDQAGGAQIVIDHLRSLCGRADPAN-EKLLTVFCGMLMNYSNENDSLQAQLINMGVIPTLVKL 188

  Fly   189 IDIGASNVEQHEDLLLNTLPLLSILTENVSDLNFDSSLNI--QLSRILAASTNPDLAEMCLELLH 251
            :.|...|....|..|:    ....|.|..|.....:|.||  :|.::.......|..||..|:|.
  Rat   189 LGIHCHNAALTEMCLV----AFGNLAELESSKEQFASTNIAEELVKLFKKQIEHDKREMIFEVLA 249

  Fly   252 YQAESDEVKLILAKDGLCETIYNLLEKYKTLASTSEARALMKLACELIVLILTGDDSMHYLY--- 313
            ..||:|.:||.|.:.||.|.:..:::: |..::..:..|.:|.|.:|:||:|.||:||..|:   
  Rat   250 PLAENDAIKLQLVEAGLVECLLEIVQQ-KVDSTKEDDLAELKTASDLMVLLLLGDESMQKLFEGG 313

  Fly   314 TTPLLKNMVDWLDSTDIDLLTTGVLALGNFARTDSHCIYFVEQQTMNKLLEVLAKNNGVKD-DVR 377
            ...:.:.::.|:.|....|...|.||:.||||.|.:||:.|:...:.||:::|.::  |:| :|.
  Rat   314 KGSVFQRVLSWIPSNSQQLQLAGALAIANFARNDGNCIHMVDNGIVEKLMDLLDRH--VEDGNVT 376

  Fly   378 LQHALLSALRNLVIPKPNKNAVIQAGLVQTILPMLEIHQPPVVFKLLGTLRMTVDGQEKLALELL 442
            :|||.|||||||.||..||..::.||:.:|:|..|:...|||.|||||||||.:|.|.:.|.:|.
  Rat   377 VQHAALSALRNLAIPVVNKAKMLSAGVTETVLKFLKSEMPPVQFKLLGTLRMLIDAQAEAAEQLG 441

  Fly   443 KNKTLIEQLVHWSKSSDYAGVTGESLRLMAWLIKHAYLSKIAYALPRKGDAPAEQIADKIPLTQD 507
            ||..|:|:||.|.::.|:|||.|||.||::.||:|:                             
  Rat   442 KNAKLVERLVEWCEAKDHAGVMGESNRLLSALIRHS----------------------------- 477

  Fly   508 YDRSSLSEFLANEGTVEAMVSMLTAQHLVMQNEALIALCILSVVYLSQPSE--AAQAQLLQ---- 566
             ....:.:.:...|.::.:|:|.|::|::||||||:||.:::.:.|. |:|  .|.|||:|    
  Rat   478 -KSKDVIKTIVQSGGIKHLVTMATSEHVIMQNEALVALALIAALELG-PAEKDLASAQLVQILHR 540

  Fly   567 ---DELVKCEVGKKLAELIS--KSSDTMTKEIVENLQ--NCVNLLKSSE 608
               ||....|:......||.  ..|:.:.|| |::|.  :.|:.|:|.|
  Rat   541 LLADERSAPEIKYNSMVLICALMGSEALHKE-VQDLAFLDVVSKLRSHE 588

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
vimarNP_995767.1 armadillo repeat 77..118 CDD:293788 11/40 (28%)
armadillo repeat 124..165 CDD:293788 9/41 (22%)
armadillo repeat 318..343 CDD:293788 6/24 (25%)
armadillo repeat 351..391 CDD:293788 18/40 (45%)
armadillo repeat 396..428 CDD:293788 15/31 (48%)
Rap1gds1NP_001401991.1 PLN03200 18..>264 CDD:215629 63/256 (25%)
armadillo repeat 44..71 CDD:293788 4/27 (15%)
Arm 86..117 CDD:425727 9/35 (26%)
armadillo repeat 91..116 CDD:293788 8/29 (28%)
armadillo repeat 124..167 CDD:293788 11/43 (26%)
ARM 346..389 CDD:214547 19/44 (43%)
armadillo repeat 351..390 CDD:293788 18/40 (45%)
armadillo repeat 395..427 CDD:293788 15/31 (48%)

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