Protein Alignment coro and coro1b

DIOPT Version :10

• Sequence 1: NP_001260743.1
• Gene: coro / 35596
• FlyBaseID: FBgn0265935
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001103177.1
• Gene: coro1b / 560168
• ZFINID: ZDB-GENE-040123-3
• Length: 499
• Species: Danio rerio
• Alignment Length: 513
• Identity: 252/513 - (49%)
• Similarity: 335/513 - (65%)
• Gaps: 30/513 - (5%)

  Fly     1 MSFR--VVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLP 63
            ||||  |||.||||||:.||.|.|.|.|::|||:.:||...||.||||:|:::|:.|||||.|||
Zfish     1 MSFRRGVVRQSKFRHVFAQAWKAEHCLDDVRVSRVTWDGPLCAANPKFIAVVIEAGGGGAFPVLP 65

  Fly    64 HNKVGRIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLV 128
            ..|.||:..:.|.|.||..||||:.||||:||||||.||||.||:||||||||...::|.||.|.
Zfish    66 LAKSGRVDQNTPTVCGHAAPVLDVQWCPHDDNVIASASEDCTVKIWQIPDGGLMSPMSEAVVTLE 130

  Fly   129 FHQRRVGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHI-DSHPDIVYSACFNWDGSKLVTT 192
            .|.:|||::.|||||||:|||||.||.:.:|:|||||::..: |:|||::||..:|.:||.|.||
Zfish   131 GHSKRVGILAWHPSALNILLTAGCDNVLCVWDVGTGELVYQLSDAHPDLIYSVSWNREGSILCTT 195

  Fly   193 CKDKKIRIYDPRTAE-LESEAMCHEGSKATRAIFLRHGLIFTTGFNRSSERQYSLRAPDALNEPI 256
            ||||.:|:.|||... |:.....|||::..||:||..|.|.||||:|.||||.:|.....|:||:
Zfish   196 CKDKALRVIDPRRGTVLKVREKAHEGTRPMRAVFLADGKILTTGFSRMSERQLALWDTRDLSEPM 260

  Fly   257 VMVELDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPK 321
            ...|:||||||:.|.||.||||.|||||||..|||||||.|.|:||:::.:.:.|||||.|.:.|
Zfish   261 ATQEMDTSNGVLLPFYDPDTNMAYLCGKGDCTIRYFEVTDESPYVHFLSLYSSKEPQRGAGFLSK 325

  Fly   322 RGCDVTTCEVAKFYRMNNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPI 386
            ||.||..||:|:||:::...: :.|||||||||||||.||||||...:.|:.||:||.|:||.|.
Zfish   326 RGVDVNKCEIARFYKLHERKV-EPISMTVPRKSDLFQGDLYPDTAGLEPALLAEDWIAGQDAPPA 389

  Fly   387 TFSLKDRVSIVQGGYVSSSVNKSLPAKKAGNILNKPRGDSASSGATSSSAGGGN----------F 441
            ..||       .|||.:       |..|.|.:..:|:..|.::.:.:|:....|          .
Zfish   390 LVSL-------SGGYTA-------PPSKGGTLRGRPKLLSPTNTSPTSTTAPANPVTVEMESEGL 440

  Fly   442 ASGNNNEASEGGPPAAVLSEKDLRTIQDEIRKLKAIIVKQENRIRALEAKEDARNKNG 499
            :.|......:||.......|..|..|..|:|.|:|:::.|.:||..|| ::.||.::|
Zfish   441 SHGRGGRDVDGGIERVKKEEDQLSDILTEVRALRALVLAQGHRIDVLE-RQLARIEDG 497

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
coro	NP_001260743.1	WD40	9..>392	CDD:475233	217/384 (57%)
		WD40 repeat	37..78	CDD:293791	20/40 (50%)
		WD40 repeat	85..129	CDD:293791	30/43 (70%)
		WD40 repeat	134..171	CDD:293791	22/37 (59%)
		WD40 repeat	178..213	CDD:293791	17/35 (49%)
		WD40 repeat	220..260	CDD:293791	19/39 (49%)
		WD40 repeat	267..308	CDD:293791	26/40 (65%)
coro1b	NP_001103177.1	WD40	11..>395	CDD:475233	217/391 (55%)
		WD40 repeat	42..81	CDD:293791	21/38 (55%)
		WD40 repeat	87..131	CDD:293791	30/43 (70%)
		WD40 repeat	136..173	CDD:293791	22/36 (61%)
		WD40 repeat	181..216	CDD:293791	17/34 (50%)
		WD40 repeat	224..264	CDD:293791	19/39 (49%)
		WD40 repeat	271..312	CDD:293791	26/40 (65%)
		WD40 repeat	319..349	CDD:293791	12/30 (40%)