Protein Alignment coro and Coro1c

DIOPT Version :10

• Sequence 1: NP_001260743.1
• Gene: coro / 35596
• FlyBaseID: FBgn0265935
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001102797.1
• Gene: Coro1c / 501841
• RGDID: 1564490
• Length: 474
• Species: Rattus norvegicus
• Alignment Length: 493
• Identity: 264/493 - (53%)
• Similarity: 342/493 - (69%)
• Gaps: 36/493 - (7%)

  Fly     4 RVVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPHNKVG 68
            ||||.||||||:|||:|.:||||:||||:.:|||:||||||:|:|||:|::|||||:|||.:|.|
  Rat     3 RVVRQSKFRHVFGQAVKNDQCYDDIRVSRVTWDSSFCAVNPRFVAIIIEASGGGAFLVLPLHKTG 67

  Fly    69 RIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLVFHQRR 133
            ||...:|.|.||.||||||.||||||.|||||||||.|.|||||:.||:.:||||||.|..|.:|
  Rat    68 RIDKSYPTVCGHTGPVLDIDWCPHNDQVIASGSEDCTVMVWQIPENGLTLSLTEPVVILEGHSKR 132

  Fly   134 VGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHIDS-HPDIVYSACFNWDGSKLVTTCKDKK 197
            ||:|.|||:|.||||:||.||.::||||||||.|:::|. |.|::|:..::.:||.:.|..||||
  Rat   133 VGIVAWHPTARNVLLSAGCDNAIIIWNVGTGEALINLDDMHSDMIYNVSWSRNGSLICTASKDKK 197

  Fly   198 IRIYDPRTAELESE-AMCHEGSKATRAIFLRHGLIFTTGFNRSSERQYSLRAPDALNEPIVMVEL 261
            :|:.|||..|:.:| ...|||::..|||||..|.:|||||:|.||||.:|..|..:.|||.:.|:
  Rat   198 VRVIDPRRQEIVAEKEKAHEGARPMRAIFLADGNVFTTGFSRMSERQLALWNPKNMQEPIALHEM 262

  Fly   262 DTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRGCDV 326
            ||||||:.|.||.||::|||||||||.|||||:|.|.|:|||:|||.:.|||||:|.|||||.||
  Rat   263 DTSNGVLLPFYDPDTSIIYLCGKGDSSIRYFEITDESPYVHYLNTFSSKEPQRGMGYMPKRGLDV 327

  Fly   327 TTCEVAKFYRMNNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPITFSLK 391
            ..||:|:|::::.. .|:.|.|||||||||||:||||||...:||:.||||.:||:||||..|||
  Rat   328 NKCEIARFFKLHER-KCEPIIMTVPRKSDLFQDDLYPDTAGPEAALEAEEWFEGKNADPILISLK 391

  Fly   392 DRVSIVQGGYVSSSVNKSLPAKKAGNILNKPRGDSASS-----GATSSSAGGGNFASGNNNEASE 451
            .       ||:... |:.|...|...:.:||..:..|.     ..|:.:
  Rat   392 H-------GYIPGK-NRDLKVVKKNILDSKPAANKKSDLICAPKKTTDT---------------- 432

  Fly   452 GGPPAAVLSEKDLRTIQDEIRKLKAIIVKQENRIRALE 489
                |:|.:|..|..|..||:.:|..|..|:.||..||
  Rat   433 ----ASVQNEAKLDEILKEIKSIKDTICNQDERISKLE 466

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
coro	NP_001260743.1	WD40	9..>392	CDD:475233	236/384 (61%)
		WD40 repeat	37..78	CDD:293791	25/40 (63%)
		WD40 repeat	85..129	CDD:293791	33/43 (77%)
		WD40 repeat	134..171	CDD:293791	24/36 (67%)
		WD40 repeat	178..213	CDD:293791	14/35 (40%)
		WD40 repeat	220..260	CDD:293791	21/39 (54%)
		WD40 repeat	267..308	CDD:293791	28/40 (70%)
Coro1c	NP_001102797.1	WD40	8..>402	CDD:475233	240/402 (60%)
		WD40 repeat	36..78	CDD:293791	26/41 (63%)
		WD40 repeat	84..128	CDD:293791	33/43 (77%)
		WD40 repeat	133..170	CDD:293791	24/36 (67%)
		WD40 repeat	178..213	CDD:293791	14/34 (41%)
		WD40 repeat	221..260	CDD:293791	21/38 (55%)
		WD40 repeat	268..309	CDD:293791	28/40 (70%)