Protein Alignment coro and coro1a

DIOPT Version :10

• Sequence 1: NP_001260743.1
• Gene: coro / 35596
• FlyBaseID: FBgn0265935
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_001005826.1
• Gene: coro1a / 448298
• XenbaseID: XB-GENE-6449552
• Length: 459
• Species: Xenopus tropicalis
• Alignment Length: 494
• Identity: 268/494 - (54%)
• Similarity: 349/494 - (70%)
• Gaps: 41/494 - (8%)

  Fly     1 MSFRVVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPHN 65
            ||.:|||:||||||:|||:|.:||||:||||:::|||.||.||||||||:||::|||||:|||.:
 Frog     1 MSRKVVRTSKFRHVFGQAVKADQCYDDIRVSQNTWDSNFCCVNPKFLAIVVEASGGGAFMVLPLS 65

  Fly    66 KVGRIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLVFH 130
            |.||:....|:|.||..|||||.||||||||||||||||.|.||:||||||:|:||||:|.|..|
 Frog    66 KTGRLDKSQPVVCGHTAPVLDIDWCPHNDNVIASGSEDCSVMVWEIPDGGLTRSLTEPLVTLEGH 130

  Fly   131 QRRVGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHIDSHPDIVYSACFNWDGSKLVTTCKD 195
            .:|||:|||||:||||||:||.||.::||:||||:.::.|::|||::|||.:|..||.|.|:|||
 Frog   131 TKRVGIVLWHPTALNVLLSAGCDNLIMIWDVGTGQGIISIETHPDLIYSAAWNLSGSLLCTSCKD 195

  Fly   196 KKIRIYDPRTAELESE-AMCHEGSKATRAIFLRHGLIFTTGFNRSSERQYSLRAPDALNEPIVMV 259
            ||||:.:||:..:|:| ...||||:..||||:....|.||||:|.||||.:|....:|.||:.:.
 Frog   196 KKIRLIEPRSGRIEAEKEKPHEGSRPVRAIFVSDDQILTTGFSRMSERQVALWDLKSLGEPLTLQ 260

  Fly   260 ELDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRGC 324
            |||||:||:.|.:|.|||::||||||||.|||||||.|||:|||::.:.:.|.|||:|.|||||.
 Frog   261 ELDTSSGVLIPFFDPDTNVVYLCGKGDSSIRYFEVTDEPPYVHYLSLYSSKESQRGMGYMPKRGL 325

  Fly   325 DVTTCEVAKFYRMNNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPITFS 389
            :|..||:|:||:::.. .|:.|.||||||||||||||||||:..|.|:|||||:.||:|||:..|
 Frog   326 EVNKCEIARFYKLHER-KCEPIIMTVPRKSDLFQEDLYPDTVGPDPALTAEEWLGGKNADPLLIS 389

  Fly   390 LKDRVSIVQGGYVSSSVNKSLPAKKAGNILNK--PRGDSASSGATSSSAGGGNFASGNNNEASEG 452
            |::       ||..|   ||...|...|:||.  |:...::...|..||
 Frog   390 LRE-------GYAPS---KSRELKVTKNVLNTRLPKRVGSNEAGTQESA---------------- 428

  Fly   453 GPPAAVLSEKDLRTIQDEIRKLKAIIVKQENRIRALEAK 491
                       |..|..||::|||.:...|.|:..||.|
 Frog   429 -----------LEQILGEIKQLKATLQGLEQRVAELEQK 456

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
coro	NP_001260743.1	WD40	9..>392	CDD:475233	238/383 (62%)
		WD40 repeat	37..78	CDD:293791	25/40 (63%)
		WD40 repeat	85..129	CDD:293791	35/43 (81%)
		WD40 repeat	134..171	CDD:293791	23/36 (64%)
		WD40 repeat	178..213	CDD:293791	19/35 (54%)
		WD40 repeat	220..260	CDD:293791	18/39 (46%)
		WD40 repeat	267..308	CDD:293791	27/40 (68%)
coro1a	NP_001005826.1	WD40	9..405	CDD:475233	244/406 (60%)
		WD40 repeat	39..79	CDD:293791	25/39 (64%)
		WD40 repeat	85..129	CDD:293791	35/43 (81%)
		WD40 repeat	134..171	CDD:293791	23/36 (64%)
		WD40 repeat	178..213	CDD:293791	19/34 (56%)
		WD40 repeat	222..261	CDD:293791	18/38 (47%)
		WD40 repeat	268..309	CDD:293791	27/40 (68%)