Protein Alignment coro and Coro2b

DIOPT Version :10

• Sequence 1: NP_001260743.1
• Gene: coro / 35596
• FlyBaseID: FBgn0265935
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_006511157.3
• Gene: Coro2b / 235431
• MGIID: 2444283
• Length: 500
• Species: Mus musculus
• Alignment Length: 509
• Identity: 220/509 - (43%)
• Similarity: 322/509 - (63%)
• Gaps: 46/509 - (9%)

  Fly     1 MSFR-VVRSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPH 64
            ||:| ..||||||:|||:|..||.|:|.|.::|:..|:.|||||.:||||:.||||||:|:|:|.
Mouse    26 MSWRPQYRSSKFRNVYGKAANREHCFDGIPITKNVHDNHFCAVNARFLAIVTESAGGGSFLVIPL 90

  Fly    65 NKVGRIAADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLVF 129
            .:.|||..::|.|.||:|.||||.|.|..||:|||.|||..|::|:||||||.|.:||.:::|..
Mouse    91 EQTGRIEPNYPKVCGHQGNVLDIKWNPFIDNIIASCSEDTSVRIWEIPDGGLKRNMTEALLELHG 155

  Fly   130 HQRRVGLVLWHPSALNVLLTAGSDNQVVIWNVGTGEILVHIDSHPDIVYSACFNWDGSKLVTTCK 194
            |.||||||.|||:..|:|.:||.|.:|:|||:..||.:..||.|.|::....||.|||.|.||||
Mouse   156 HSRRVGLVEWHPTTNNILFSAGYDYKVLIWNLDIGEPVKMIDCHTDVILCMSFNTDGSLLTTTCK 220

  Fly   195 DKKIRIYDPRTAELESEAMCHEGSKATRAIFLRH-GLIFTTGFNRSSERQYSLRAPDALNEPIVM 258
            |||:|:.:||:..:..||.| :..:..|.:||.: ..:.|||.:|.:.||.:|...:.|:.|::.
Mouse   221 DKKLRVIEPRSGRVLQEANC-KNHRVNRVVFLGNMKRLLTTGVSRWNTRQIALWDQEDLSMPMIE 284

  Fly   259 VELDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRG 323
            .|:|..:|::||.|||||:|:||.||||..|||:|::.|.|::.|:..|::..||:|:|:|||.|
Mouse   285 EEIDGLSGLLFPFYDADTHMLYLAGKGDGNIRYYEISTEKPYLSYLMEFRSPAPQKGLGVMPKHG 349

  Fly   324 CDVTTCEVAKFYRM-NNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPIT 387
            .||:.|||.:||:: ...||.:.|||.|||:||.:|||:||.|...:.|:|.:||:.|.:.||:.
Mouse   350 LDVSACEVFRFYKLVTLKGLIEPISMIVPRRSDSYQEDIYPMTPGTEPALTPDEWLGGINRDPVL 414

  Fly   388 FSLKDRVSIVQGGY-VSSSVNKSLPAKKAGNILNKPRGDSASSGATSSSAGGGNFASGNNNEASE 451
            .|||:       || .||.|....|.::..:::                        .|..:..|
Mouse   415 MSLKE-------GYKKSSKVVFKAPIREKKSVV------------------------VNGIDLLE 448

  Fly   452 GGPPAAVLSEKDLRTI----QDEIRKLKAIIVKQENRIRALEAK-EDARN--KN 498
            ..||.   :|.:|..:    |||||:||..:.:::.|:|.|:.: ::.||  ||
Mouse   449 NVPPR---TENELLRMFFRQQDEIRRLKEELAQKDIRLRQLQLELKNLRNNPKN 499

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
coro	NP_001260743.1	WD40	9..>392	CDD:475233	188/384 (49%)
		WD40 repeat	37..78	CDD:293791	22/40 (55%)
		WD40 repeat	85..129	CDD:293791	25/43 (58%)
		WD40 repeat	134..171	CDD:293791	18/36 (50%)
		WD40 repeat	178..213	CDD:293791	17/34 (50%)
		WD40 repeat	220..260	CDD:293791	12/40 (30%)
		WD40 repeat	267..308	CDD:293791	21/40 (53%)
Coro2b	XP_006511157.3	WD40	35..480	CDD:475233	208/479 (43%)
		WD40 repeat	65..105	CDD:293791	23/39 (59%)
		WD40 repeat	111..155	CDD:293791	25/43 (58%)
		WD40 repeat	160..197	CDD:293791	18/36 (50%)
		WD40 repeat	204..239	CDD:293791	17/34 (50%)
		WD40 repeat	245..282	CDD:293791	11/36 (31%)
		WD40 repeat	290..332	CDD:293791	22/41 (54%)