Protein Alignment coro and coro2a

DIOPT Version :10

• Sequence 1: NP_001260743.1
• Gene: coro / 35596
• FlyBaseID: FBgn0265935
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: XP_002936730.2
• Gene: coro2a / 100485579
• XenbaseID: XB-GENE-492690
• Length: 532
• Species: Xenopus tropicalis
• Alignment Length: 529
• Identity: 201/529 - (37%)
• Similarity: 316/529 - (59%)
• Gaps: 42/529 - (7%)

  Fly     7 RSSKFRHVYGQALKREQCYDNIRVSKSSWDSTFCAVNPKFLAIIVESAGGGAFIVLPHNKVGRIA 71
            ||||:|||:|:...:|.|||.:.:::|..|:.||||||.|:|::.|.||||||||:|..:.|::.
 Frog    13 RSSKYRHVFGKPANKESCYDCVPITRSVQDNHFCAVNPVFIAVVTECAGGGAFIVIPLQQSGKLD 77

  Fly    72 ADHPLVGGHKGPVLDIAWCPHNDNVIASGSEDCVVKVWQIPDGGLSRTLTEPVVDLVFHQRRVGL 136
            ..||.|.||:|.||||.|.|.:|.||||.|||..||:|.||...|::.||:|..:|:.|.|||||
 Frog    78 PHHPKVCGHRGNVLDIKWNPFDDYVIASCSEDATVKIWDIPRHLLNKNLTDPRKELLGHTRRVGL 142

  Fly   137 VLWHPSALNVLLTAGSDNQVVIWNVGTGEILVH-----IDSHPDIVYSACFNWDGSKLVTTCKDK 196
            :.|||:|.|::.:.|.|.:::|||:...:.:::     |:.|.|::.|..||.|||.|.|:|||:
 Frog   143 IEWHPTASNIIFSTGYDYKIMIWNIDNDDPVIYSPVRTIECHKDVILSMSFNTDGSLLATSCKDR 207

  Fly   197 KIRIYDPRTAELESEAMCHEGSKATRAIFLRH-GLIFTTGFNRSSERQYSLRAPDALNEPIVMVE 260
            .||:.|||...:..|:.| :..||::.:||.: .::.::|.:|.:.||.:|...:.|:.|:...:
 Frog   208 IIRVIDPRQGTIIQESNC-KTHKASKVLFLGNMNMLLSSGTSRWNNRQAALWDQNDLSVPLHQED 271

  Fly   261 LDTSNGVMFPLYDADTNMIYLCGKGDSVIRYFEVTPEPPFVHYINTFQTTEPQRGIGLMPKRGCD 325
            ||.|:|::||.||.||||:|:.||||..|||:||..:.|::.|:|.:::..||:|||::||||.|
 Frog   272 LDGSSGLIFPFYDCDTNMLYIVGKGDGNIRYYEVCSQKPYLQYLNEYRSNLPQKGIGVLPKRGVD 336

  Fly   326 VTTCEVAKFYRM-NNNGLCQVISMTVPRKSDLFQEDLYPDTLAEDAAITAEEWIDGKDADPITFS 389
            |:||||.:||:: ....|.:.:||.|||:|:.:|:|:||.|.....|:||.||:||.:..|:..|
 Frog   337 VSTCEVFRFYKLVTIKSLIEPVSMIVPRRSESYQDDIYPMTTGTQPALTAREWLDGINRGPVLMS 401

  Fly   390 LK--DRVSIVQGGYVSSSVNKSLPAKK-------------------AGNILNKPRGDSASSGATS 433
            ||  .:.:..|...........:|.|:                   ...|:.:.|.:..:.....
 Frog   402 LKPGSKSAPYQVPVTKEEPKFPIPIKEPKLMYEGKVPTRTLWEIEYKTEIIREDRSNKKAFERLQ 466

  Fly   434 SSAGGGNFASGNNNEASEGGPPAAVLSEKDLRTI----QDEIRKLKAIIVKQENRIRALEAKEDA 494
            .|    ..|..|..:..|...|.   :|.:|..:    |:|||:|:..|.:::.:|:.||.  :.
 Frog   467 DS----KQAISNGFDFFECPAPK---TENELLQMFYKQQEEIRRLRDQITQRDVQIKQLEL--EI 522

  Fly   495 RNKNGSDAA 503
            :||..|.|:
 Frog   523 KNKRNSTAS 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
coro	NP_001260743.1	WD40	9..>392	CDD:475233	174/391 (45%)
		WD40 repeat	37..78	CDD:293791	21/40 (53%)
		WD40 repeat	85..129	CDD:293791	23/43 (53%)
		WD40 repeat	134..171	CDD:293791	13/41 (32%)
		WD40 repeat	178..213	CDD:293791	17/34 (50%)
		WD40 repeat	220..260	CDD:293791	10/40 (25%)
		WD40 repeat	267..308	CDD:293791	21/40 (53%)
coro2a	XP_002936730.2	WD40	15..523	CDD:475233	195/517 (38%)
		WD40 repeat	45..85	CDD:293791	22/39 (56%)
		WD40 repeat	91..135	CDD:293791	23/43 (53%)
		WD40 repeat	140..182	CDD:293791	13/41 (32%)
		WD40 repeat	189..224	CDD:293791	17/34 (50%)
		WD40 repeat	230..271	CDD:293791	10/40 (25%)
		WD40 repeat	278..305	CDD:293791	16/26 (62%)