DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zip42C.2 and Slc39a12

DIOPT Version :9

Sequence 1:	NP_610231.2	Gene:	Zip42C.2 / 35580	FlyBaseID:	FBgn0033097	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	NP_001012305.1	Gene:	Slc39a12 / 277468	MGIID:	2139274	Length:	689	Species:	Mus musculus

Alignment Length:	312	Identity:	57/312 - (18%)
Similarity:	108/312 - (34%)	Gaps:	89/312 - (28%)

- Green bases have known domain annotations that are detailed below.

  Fly    71 LPEVVEVVNALQ---DC--RMLAPTPFGLPEVLL----CTGFYLMYCIEETMHFVVRRR------ 120
            ||::...:.||.   .|  |...|:|....|.:.    .|....:..||:.::.:..||
Mouse   204 LPQLAATIIALSLQGVCLGRKALPSPDDFTEYIFSFLNSTNTLHLSEIEQLLNMLTTRRTCAKED 268

  Fly   121 ------QQRKLREVVTIKDAGEELRTEIVVQPEESPKEPNWLRGLGIIVALSLHELF----GGMA 175
                  |:::..|..:::|.    :|...:..|.....|:|  ......|..|.|:|    ..::
Mouse   269 KYLHQYQRKQNTEEHSLRDP----KTSTAMDKESDDHSPSW--DQACFSARQLVEIFLQNHSSLS 327

  Fly   176 IGLE------------------------------MSVSTVWFMTGAISVHKLVLAFCIGMEIMMA 210
            |..|                              .::....:.|.|:::  |.|...:|..:::.
Mouse   328 ISKEDFKQLSPGIIQQLLSCSCQMPKDQQAKPPPTTLEKYGYSTVAVTL--LTLGSMLGTALVLF 390

  Fly   211 HTRWLLAVVYLLVFSIVTPIGVG--------------IGIAVSESAAANQPSTVS------GILQ 255
            |:   ....|.|:..:...:.||              :|:...|:...:...:.|      |:|.
Mouse   391 HS---CEENYSLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAEFGHFHESQSPIWKLLGLLG 452

  Fly   256 GLACGTLIYVVFFEIVAKNHAGIRILLSSMVGFVLMFGLQIAIGE--AKGKS 305
            |:....||...|..:|:.|..|:. |::..||.....||...:.:  :.|||
Mouse   453 GIHGFFLIEKCFILLVSPNTKGLP-LVNEHVGHTHHLGLNPELNDQSSGGKS 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zip42C.2	NP_610231.2	Zip	9..294	CDD:280666	52/297 (18%)
Slc39a12	NP_001012305.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	275..303		5/31 (16%)
		Zip	369..681	CDD:280666	30/141 (21%)
		XEXPHE-motif. /evidence=ECO:0000250	578..583
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910