DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Zip42C.2 and AgaP_AGAP011178

DIOPT Version :9

Sequence 1:	NP_610231.2	Gene:	Zip42C.2 / 35580	FlyBaseID:	FBgn0033097	Length:	310	Species:	Drosophila melanogaster
Sequence 2:	XP_309469.4	Gene:	AgaP_AGAP011178 / 1270749	VectorBaseID:	AGAP011178	Length:	398	Species:	Anopheles gambiae

Alignment Length:	355	Identity:	130/355 - (36%)
Similarity:	194/355 - (54%)	Gaps:	61/355 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 DQHLIVAKIVAIVVLFLVTLIFCFIPYLLDRFYKWTQRPENNAREFKVVLCLLNFGGGVLIATTF 67
            |....:||:.::||||.|:::...:|:.|.|::.......:......::..||:||||.|::|||
Mosquito    36 DDSPTIAKVTSMVVLFSVSMVCGLVPFKLVRWFNLNPATPSGGTHLFLIRLLLSFGGGALLSTTF 100

  Fly    68 IHMLPEVVEVVNALQDCRML-AP--TPFGLPEVLLCTGFYLMYCIEETMHFVVRRRQQRKLREV- 128
            :|:|||:...:.||.:...| ||  .||.|.|.||.:||:::|..||.:|:.:.||.....|..
Mosquito   101 LHLLPEINHSIEALVETGALPAPDELPFPLGEFLLTSGFFMIYLTEELVHWWMHRRSANARRIAR 165

  Fly   129 -----------------------------------------VTIKDAGEELRTEIVVQPEESPKE 152
                                                     ||..|..:.:.:.:.|.|..|...
Mosquito   166 SEKTAPGGSSTMVPIDGGASKHDHAHGHSHLPIGNVTAVYPVTDVDGTQVVPSVVPVPPAPSANG 230

  Fly   153 PNWLRGLGIIVALSLHELFGGMAIGLEMSVSTVWFMTGAISVHKLVLAFCIGMEIMMAHTRWLLA 217
            |  ||||.|::|||:||||.|:|:|||.|.|.||.:.||::.||.|:|||:..|:::|..|:.:|
Mosquito   231 P--LRGLLIVLALSIHELFEGLAVGLERSPSAVWLLFGAVASHKFVIAFCVAFELLVASVRFRIA 293

  Fly   218 VVYLLVFSIVTPIGVGIGIAVSE-SAAANQP-STVSGILQGLACGTLIYVVFFEIVAK----NHA 276
            |:|:.|:|:|:|:|:|||||:|. |:..||. ..||.:|||||.||||||:||||:||    :||
Mosquito   294 VLYIFVYSVVSPVGIGIGIALSSVSSDTNQTIEVVSVVLQGLASGTLIYVIFFEILAKDAGHSHA 358

  Fly   277 GIRILLSSMVGFVLMFGLQIAIGEAKGKSH 306
            ...|:|:..:...|.|        |.|.||
Mosquito   359 NGTIILTICLLTFLCF--------AAGHSH 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Zip42C.2	NP_610231.2	Zip	9..294	CDD:280666	125/335 (37%)
AgaP_AGAP011178	XP_309469.4	Zip	41..373	CDD:280666	123/333 (37%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1558
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H44230
Inparanoid	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28706
OrthoDB	1	1.010	-	-		D471714at33208
OrthoFinder	1	1.000	-	-		FOG0000574
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11040
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X561
TreeFam	1	0.960	-	-
	9	8.890