DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment chk and ATG22

DIOPT Version :9

Sequence 1:	NP_001163063.1	Gene:	chk / 35578	FlyBaseID:	FBgn0033095	Length:	894	Species:	Drosophila melanogaster
Sequence 2:	NP_009892.1	Gene:	ATG22 / 850319	SGDID:	S000000543	Length:	528	Species:	Saccharomyces cerevisiae

Alignment Length:	197	Identity:	46/197 - (23%)
Similarity:	72/197 - (36%)	Gaps:	69/197 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   137 YGWVVVFAS---------LVVSLIA-----DGLS--------FS--------FGLINVELLEYFG 171
            ||||.:|.|         :::.|||     |.::        ||        ..||.:.:|....
Yeast   301 YGWVSLFESFKHARLLKDVMIFLIAWFIISDSITTINSTAVLFSKAELHMSTLNLIMISVLTVVN 365

  Fly   172 ES----------TSKTAWISS--LFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSF 224
            ..          .:|..|.||  |.:.:      ||::.:..||     |||...:|||..
Yeast   366 AMLGAFMIPQFLATKFRWTSSQTLMYII------IWASFIPFYG-----ILGFFFNAFGLK---- 415

  Fly   225 CNSIEMLMVTFGIISGLGLGIGYVTAVVSIAFWF----DKKRTFATGIGASGTG---IGTFVYAR 282
             :..||.::..    ..||.:|.::||....|..    .|:.||.:....:..|   :|.|:...
Yeast   416 -HKFEMFLLAI----WYGLSLGGLSAVSRSVFSLIVPPGKESTFFSMFSITDKGSSILGPFLVGL 475

  Fly   283 LT 284
            ||
Yeast   476 LT 477

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	42/191 (22%)
chk	NP_001163063.1	MFS	<685..869	CDD:119392
ATG22	NP_009892.1	MFS_Atg22_like	28..484	CDD:341036	46/197 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.100