Protein Alignment chk and CG8468

DIOPT Version :10

• Sequence 1: NP_610230.3
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_610940.1
• Gene: CG8468 / 36577
• FlyBaseID: FBgn0033913
• Length: 678
• Species: Drosophila melanogaster
• Alignment Length: 799
• Identity: 191/799 - (23%)
• Similarity: 308/799 - (38%)
• Gaps: 192/799 - (24%)

  Fly   103 GQVKRRKRLI--SNESGDSIDSSSTEKKTPKMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVE 165
            |.|.::...|  .||..:.|:.::.  ..|  ||.|:.|||:.||.:...:.||:.|..|||..:
  Fly    16 GLVSKQPENIKEENEGEEEIEEAAV--VVP--PDSGWAWVVMVASFLCCTVIDGIVFCSGLIQEQ 76

  Fly   166 LLEYFGESTSKTAWISSLFFSVPLLMGPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEM 230
            |:..||.|.:..|::|||.....|:.||..|.:.:::|.|.:||.|.:.:|..|.||.|..|:|.
  Fly    77 LMAEFGVSKAYVAFVSSLLSGCYLMAGPFVSAMANRFGFRPVTITGAIFAAICFGLSYFATSVEY 141

  Fly   231 LMVTFGIISGLGLGIGYVTAVVSIAFWFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRG 295
            |.:.:|::.|:|..:.|:.|||.|.|:|:|.|..|||:...|:|:||||:|.||..|::| |||
  Fly   142 LFLIYGVLGGIGFCMVYIPAVVIIGFYFEKWRALATGVAMCGSGVGTFVFAPLTKILLKS-GWR- 204

  Fly   296 ATLILGGTMLNACVCGALMRDPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVL 360
            .||.:.|.::.:|....|...|        ::..:.|||   |.....:|.|||
  Fly   205 YTLAIQGIIVLSCALFGLAFRP--------IQPITLSVT---NEEGDEQEKKKL----------- 247

  Fly   361 DSLVTKNNTEANQQIDDPLDSALKRYRSEIFLPTFLSTQELDSICEVKSLSRRSLRHKEGEEAPS 425
                   |...|                     |...|.:|......|.|       .||..|.|
  Fly   248 -------NGHGN---------------------TVAPTPQLHQAAFTKPL-------PEGRFAYS 277

  Fly   426 RENLLSMSSGAGAYPPSTAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNG 490
            ..|                   |..:|.||.........|::.:          :..:..|.|:|
  Fly   278 MPN-------------------SAHNTYMGASQRNHYPTAQEIF----------KGMNLERRPSG 313

  Fly   491 SLRSSDEGYLTQKHASSRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETF 555
            :.:.|....|.|...|            :.|||:....::....|..:..:.|:
  Fly   314 TAQGSKGTELKQLRKS------------QPTTPNGDPQQLTFNLHKELTTVGEN----------- 355

  Fly   556 ALLEPSRRIRPTVIAIPEQEQSVNSEL-------ATRRARLDSITGIR------RLSRSKKPSHH 607
                              :|::.|..|       .|.:||..:::|.|      |.:.:...:||
  Fly   356 ------------------EEEAENDNLLETEAKPVTIQARRHTVSGRRPQDIGKRSAAAAHEAHH 402

  Fly   608 RSNLRRNISIRNSNFLKDMRIHRNSIHYRGAMLNTHRYRLRASSCPNIYRNSMTTIAKEEEDTWY 672
                       ..:......::|:.|.:.|::....:|:.:.|..   |..|:|.:..::
  Fly   403 -----------GQSHSSSRPMYRDDIFFSGSLTRIPQYQSQTSLA---YHMSVTRLPTKQ----- 448

  Fly   673 DNFVD--------------TMKSIFDFSLFLDMKFALFNLSTLFLFIWFIIPYLYLPDYMKQYKY 723
            |...|              |:.::.|.:|.....|.....|.....:.|.:|:.:|.|..|....
  Fly   449 DMLEDRQKGCRICPEAVRRTLSTMLDTTLLKSPAFMCLAFSGFLTMMGFFVPFTFLVDRAKAAGM 513

  Fly   724 DVSQSAELISDVGIAQTVGMIGLGYLGDLS-----WMNINICYSLCMLVCGASVFFMPLLITNYM 783
            |...:..::|.:|:..|...|..|.|....     |:| |..     |..|........::.|..
  Fly   514 DEQAAYGVLSGIGVVNTFARIVCGSLSSFPAVKPLWLN-NFA-----LTAGGIATICSGIVINTA 572

  Fly   784 GLMVMCVIFGFTFASSFSFTPSILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRW 848
            ......:.||...|...:....|.|.::.|:..|.|||.::|.||:....|.||||.:|..||.:
  Fly   573 TQWTFALFFGICIACFSALRSLIAVELIGLEKLTNAYGFLMLFQGLAATFGSPIAGGLYVMTGSY 637

  Fly   849 DDTFYYAGIFIALSGVCSY 867
            :..||:||..|.||....|
  Fly   638 NAAFYFAGGLILLSAFLCY 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_610230.3	MFS_MCT_SLC16	138..>315	CDD:340910	70/176 (40%)
		MFS	<687..869	CDD:475125	50/186 (27%)
CG8468	NP_610940.1	MFS_MCT_SLC16	49..>225	CDD:340910	70/177 (40%)
		MFS	<477..658	CDD:475125	50/186 (27%)