Protein Alignment chk and mct-5

DIOPT Version :9

• Sequence 1: NP_001163063.1
• Gene: chk / 35578
• FlyBaseID: FBgn0033095
• Length: 894
• Species: Drosophila melanogaster
• Sequence 2: NP_495464.2
• Gene: mct-5 / 187995
• WormBaseID: WBGene00020168
• Length: 591
• Species: Caenorhabditis elegans
• Alignment Length: 803
• Identity: 192/803 - (23%)
• Similarity: 311/803 - (38%)
• Gaps: 261/803 - (32%)

  Fly   127 KKTPKMPDGGYGWVVVFASLVVSLIADGLSFSFGLINVELLEYFGESTSKTAWISSLFFSVPLLM 191
            |..|..||||:|||||..|..:.:.|||..:|||::..:|:..|..:.:.|:.|.|:.....|..
 Worm     9 KLVPLPPDGGWGWVVVIGSFFIHVFADGFVYSFGILAEKLMIEFNSNNTMTSLIVSMLTGFTLGA 73

  Fly   192 GPIWSNLVDKYGCRKMTILGGVVSAFGFALSSFCNSIEMLMVTFGIISGLGLGIGYVTAVVSIAF 256
            ||:.|.:.:|||||..||:|..|:..|..||.|...|...:::.|:|.|:|.|:.|..|:|.:..
 Worm    74 GPLASAVCNKYGCRITTIIGAGVAFVGCLLSCFATEIWHFVISVGVIMGIGFGLVYCPAIVIVTM 138

  Fly   257 WFDKKRTFATGIGASGTGIGTFVYARLTSYLIESYGWRGATLILGGTMLNACVCG--------AL 313
            :|:.||:.||||..:|.|:|..|:..:.:::|.:||||...::....::...|||        ||
 Worm   139 YFESKRSLATGIAVAGAGVGAVVFGPINTFIISNYGWRYVFVLFLFVIILCAVCGATFVPLQFAL 203

  Fly   314 MRDPDWLIEENRLESRSQSVTTFSNSSVCLEEIKKLLDTGITKEAVLDSLVTKNNTEANQQIDDP 378
            :.|.|...|.|               .|..:|:||:                    :.|
 Worm   204 VPDDDDDGEYN---------------DVFEDEVKKI--------------------DYN------ 227

  Fly   379 LDSALKRYRSEIFL--PTFLSTQELDSICEVKSLSRRSLRHKEGEEAPSRENLLSMSSGAGAYPP 441
                 ||:..::.|  |..:..:.:...|:::         |..:.|                .|
 Worm   228 -----KRFEEKVSLLSPPQVLERSMSQCCDIQ---------KNNQHA----------------RP 262

  Fly   442 STAVIGSPDDTLMGGIAHEAAEEAKKAYLASIETLSPSEKRSTGRTPNGSLRSSDEGYLTQKHAS 506
            |::| |:.|                      :|.|.        |...|::...:.|||.:|
 Worm   263 SSSV-GAVD----------------------LEPLL--------RPRCGTIGERNSGYLNRK--- 293

  Fly   507 SRYSLNENIFMAKHTTPSISNLKVNGLRHNSVDILSEDMHCYYSKDETFALLEPSRRIRPTVIAI 571
                   ::|.    |.||||
 Worm   294 -------DVFY----TGSISN-------------------------------------------- 303

  Fly   572 PEQEQSVNSELATRRARLDSITGIRRLSRSKKPSHHRSNLRRNISIRNSNFLKDMRIHRNSIHYR 636
                      :|..||               .|..:||.                    .|:|
 Worm   304 ----------VAEFRA---------------NPDKYRST--------------------GSLH-- 321

  Fly   637 GAMLNTHRY--------RLRASSCPNIYRNSMTTIAKEEEDTWYD-----NFVDTMKSIFDFSLF 688
             ..||.|.:        |.....|.    .|:..:.:::|..:.|     |...|:.::|.|.|.
 Worm   322 -TALNIHTHHTGTVGDDRESGHGCD----QSLDGMNEKKETDFMDDIEGSNMFKTINNMFSFQLL 381

  Fly   689 LDMKFALFNLSTLFLFIWFIIPYLYLPDYMKQYKYDVSQSAELISDVGIAQTVGMIGLGYLGDLS 753
            ||..|.||.:|.|...:.|..|..:||.::.....|.:.|..::|..|.|.|:|.:..|.:.|..
 Worm   382 LDPAFLLFAISNLLTSVGFNSPLYFLPLHVTNILSDNNVSGNILSVYGTANTIGRLIFGVVADQK 446

  Fly   754 ----------------WMNINICYSLCMLVCGASVFFMPLLITNYMGLMVMCVIFGFTFASSFSF 802
                            ||     |::.:.:||....|. .....|:.|.:..|:||||.||....
 Worm   447 LPLPAGLGDDTARNRLWM-----YNISLTICGIVTAFC-YKFDGYILLDIYAVLFGFTIASYVCL 505

  Fly   803 TPSILVSIVDLDDFTCAYGLVLLVQGVGMIAGPPIAGVIYEYTGRWDDTFYYAGIFIALSGVCSY 867
            |..|||.::.||..|.|:||:||.||||.:.||.::|.:.:.||.:..:|.:.||.:.:||:..:
 Worm   506 TSVILVDLLGLDKLTNAFGLLLLWQGVGTVIGPLVSGYLADLTGNYTLSFVFCGINLMVSGLMLF 570

  Fly   868 LIEFCEKKAPKESDSDVLETKKA 890
            :|.:.::|    .|.||...:::
 Worm   571 VIPYFKRK----DDVDVSNKQRS 589

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
chk	NP_001163063.1	MFS	143..>315	CDD:119392	59/179 (33%)
		MFS	<685..869	CDD:119392	63/199 (32%)
mct-5	NP_495464.2	MFS_MCT_SLC16	20..573	CDD:340910	181/770 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2504
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000033
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11360
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X70
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.910