Protein Alignment Rab2 and RAB5B

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_001401387.1
• Gene: RAB5B / 5869
• HGNCID: 9784
• Length: 296
• Species: Homo sapiens
• Alignment Length: 219
• Identity: 80/219 - (36%)
• Similarity: 124/219 - (56%)
• Gaps: 38/219 - (17%)

  Fly     7 FKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQEAFRSI 71
            ||.:::|::.||||.|:|:|...:|....:.|||..|..:.:.:|...:|.:||||||||.:.|:
Human   102 FKLVLLGESAVGKSSLVLRFVKGQFHEYQESTIGAAFLTQSVCLDDTTVKFEIWDTAGQERYHSL 166

  Fly    72 TRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKKEEGEA 136
            ...|||||..|::|||||.:|||....||:::.::.::.::||.|.|||:||.::|.|:.||.:|
Human   167 APMYYRGAQAAIVVYDITNQETFARAKTWVKELQRQASPSIVIALAGNKADLANKRMVEYEEAQA 231

  Fly   137 FAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGQQHSPTNPSLPGA 201
            :|.::.|:||||||:||.||.:.|:..||::                     .:..|.|     .
Human   232 YADDNSLLFMETSAKTAMNVNDLFLAIAKKL---------------------PKSEPQN-----L 270

  Fly   202 GGAAGAA------------NSGCC 213
            |||||.:            .|.||
Human   271 GGAAGRSRGVDLHEQSQQNKSQCC 294

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	78/217 (36%)
RAB5B	NP_001401387.1	Rab5_related	101..263	CDD:206653	70/181 (39%)