Protein Alignment Rab2 and Rab4a

DIOPT Version :10

• Sequence 1: NP_477090.1
• Gene: Rab2 / 35577
• FlyBaseID: FBgn0014009
• Length: 213
• Species: Drosophila melanogaster
• Sequence 2: NP_033029.2
• Gene: Rab4a / 19341
• MGIID: 105069
• Length: 218
• Species: Mus musculus
• Alignment Length: 216
• Identity: 115/216 - (53%)
• Similarity: 148/216 - (68%)
• Gaps: 11/216 - (5%)

  Fly     2 SYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQE 66
            :|.:|||:::||:.|.||||||.||.:|:|:...:.|||||||:::|.:.||.:|||||||||||
Mouse     9 TYDFLFKFLVIGNAGTGKSCLLHQFIEKKFKDDSNHTIGVEFGSKIINVGGKYVKLQIWDTAGQE 73

  Fly    67 AFRSITRSYYRGAAGALLVYDITRRETFNHLTTWLEDARQHSNSNMVIMLIGNKSDLDSRREVKK 131
            .|||:||||||||||||||||||.|||:|.||.||.|||..::.|:|::|.|||.|||:.|||..
Mouse    74 RFRSVTRSYYRGAAGALLVYDITSRETYNALTNWLTDARMLASQNIVLILCGNKKDLDADREVTF 138

  Fly   132 EEGEAFAREHGLVFMETSARTAANVEEAFINTAKEIYEKIQEGVFDINNEANGIKIG-----QQH 191
            .|...||:|:.|:|:||||.|..||||||:..|::|..||:.|..|.....:||:.|     |..
Mouse   139 LEASRFAQENELMFLETSALTGENVEEAFMQCARKILNKIESGELDPERMGSGIQYGDAALRQLR 203

  Fly   192 SPTNPSLPGAGGAAGAANSGC 212
            ||.....|      .|...||
Mouse   204 SPRRTQAP------SAQECGC 218

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Rab2	NP_477090.1	PLN03108	1..213	CDD:178655	115/216 (53%)
Rab4a	NP_033029.2	Rab4	14..174	CDD:206696	98/159 (62%)
		Switch 1. /evidence=ECO:0000250|UniProtKB:P61106	44..49		3/4 (75%)
		Switch 2. /evidence=ECO:0000250|UniProtKB:P61106	70..79		7/8 (88%)