Protein Alignment Pld and Pld

DIOPT Version :10

• Sequence 1: NP_001137610.1
• Gene: Pld / 35554
• FlyBaseID: FBgn0286511
• Length: 1364
• Species: Drosophila melanogaster
• Sequence 2: XP_061515232.1
• Gene: Pld / 1272489
• VectorBaseID: AGAMI1_009563
• Length: 1293
• Species: Anopheles gambiae
• Alignment Length: 1340
• Identity: 709/1340 - (52%)
• Similarity: 891/1340 - (66%)
• Gaps: 150/1340 - (11%)

  Fly    89 DAGTVGGALPPYALTNSDEE--HGSGEEDASEENSNNEEGEGVFRDCTDEAVVEHHNRCLPEFQF 151
            |.||....|    ....|::  ||:....|....:....|:|............||:..|..:..
Mosquito    40 DTGTASSNL----TAQLDQQGCHGTDSRGAYYNGTTGGSGDGGAGGGAGAGSAGHHDASLACYSI 100

  Fly   152 SLVDSEYDETLAFPDSVTILSNVGDKPVLVERKETDDDEEEFDDEENNSVVLRHEIPFTSIYGPS 216
            .....||||.|..|||||.||..|:.||||.| |:|.|          ||....|||::.:|...
Mosquito   101 RSEPEEYDENLDAPDSVTYLSIGGNNPVLVIR-ESDAD----------SVSPASEIPYSYVYNTP 154

  Fly   217 VKFNSFQRKVFIPGREIHVRIVDTERSVTTHLLNPNLYTIELTHGPFKWTIKRRYKHFNSLHQQL 281
            |||:|.:|.:||||.||.|.|:|.|||:|:|:|||||||::||||||.|||::||.||.:|||||
Mosquito   155 VKFDSMRRHIFIPGLEIIVEIIDYERSLTSHVLNPNLYTVKLTHGPFSWTIQKRYNHFRNLHQQL 219

  Fly   282 SFFRTSLNIPFPSRSHKEKRTTLKATAREMADESTLKDLPSHTKVKQTSTPLRAEGRSSKIAGSN 346
            :.:|.||:||||::||||:|.:.    |.|           ||..:.|::|
Mosquito   220 TTYRASLHIPFPTKSHKERRDSF----RNM-----------HTVHQATASP-------------- 255

  Fly   347 ANNAMAMISPNHSSILAGLTPRRIQKKRKKKKKRKLPRFPNRPESLVTVENLSVRIKQLEDYLYN 411
                 ||             .:::.|..||.||..|||||.:|:|||:.:.:..||||||:||||
Mosquito   256 -----AM-------------QQKLGKPLKKIKKSALPRFPLKPDSLVSFDAIPQRIKQLEEYLYN 302

  Fly   412 LLNISLYRSHHETLNFVEVSNVSFVPGMGIKGKEGVILKRTGSTRPGQAGCNFFGCFQKNCCVRC 476
            ||||||||:.|.|:||:|||::||:..:|.|||||.|.||||||||||:||||.||....|||||
Mosquito   303 LLNISLYRNFHGTINFLEVSHISFISALGEKGKEGPIKKRTGSTRPGQSGCNFCGCLAGGCCVRC 367

  Fly   477 NYFCSDVVCGTWRNRWFFVKETCFGYIRPTDGSIRAVILFDQGFDVSTGIYQTGMRKGLQVLTNN 541
            :|||:||:...|||||||||||||||.||.||.:|.|:|||||||:|:|:|.||||.|||:.||:
Mosquito   368 SYFCTDVLWSKWRNRWFFVKETCFGYYRPKDGVLRCVVLFDQGFDISSGMYSTGMRNGLQIATNS 432

  Fly   542 RHIVLKCWTRRKCKEWMQYLKNTANSYARDFTLPNPHMSFAPMRANTHATWYVDGAQYMSAVADG 606
            |::|:|..|||..||||.::|..||..||||||||||.||||.|....|.|:||||.|||||||.
Mosquito   433 RYLVIKYPTRRIAKEWMTHMKRVANESARDFTLPNPHQSFAPSRPGVQAGWFVDGAGYMSAVADA 497

  Fly   607 LEAALEEIYIADWWLSPEIYMKRPALDGDYWRLDKILLRKAEQGVRVFVLLYKEVEMALGINSYY 671
            ||.|.|||:|.||.|||||||||||:|||||||||||.||||||:::||||:||::.||||||||
Mosquito   498 LEGATEEIFITDWMLSPEIYMKRPAIDGDYWRLDKILKRKAEQGIKIFVLLFKELDFALGINSYY 562

  Fly   672 SKSTLA-KHENIKVMRHPDHARGGILLWAHHEKIVVIDQTYAFMGGIDLCYGRWDDHHHRLTDLG 735
            ||:.|. :||||||||||||||.|||.||||||:|:|||||||:||||||||||||:.|||||||
Mosquito   563 SKAKLVEQHENIKVMRHPDHARAGILFWAHHEKLVIIDQTYAFVGGIDLCYGRWDDYQHRLTDLG 627

  Fly   736 SIST---SSFSGSTRRTPSLYFTKDDTDSAFGSRKSSRNAHYDTSAKERPPS-----------PP 786
            |||:   ||.:.:|.|.||.....|:..|.....|||:|....|:...:.|:           |.
Mosquito   628 SISSSTNSSANNTTTRKPSTVVELDENGSVANLLKSSKNIAIATAVDRQAPTSVAVKRADTTQPA 692

  Fly   787 PDEP-------NTSIELKTLKPG------DRLLIPSTLVSSPGETPAESGIAL-EGMKLNTPEME 837
            ..||       ....|.....||      ||:|..:.|..: .:.|.|....| |.:|.||||||
Mosquito   693 AKEPVATNGKQKNPAEKNPEAPGAMGDPPDRVLQAAALALT-DQLPLEERDELPENIKQNTPEME 756

  Fly   838 RKNVLDRLKNNAMKGARMGKDFMHRLTATETEEKSAEVYTIESEEATDHEVNLNMASGGQEVAIT 902
            |:|::..:|:       ||:|..:|:|.:|         .::..:.||...:.....||..|...
Mosquito   757 RRNIMGMIKD-------MGRDLKNRITLSE---------HLDHPQGTDALASGGATGGGSGVKSN 805

  Fly   903 TSSTQILS---------------------------------EFCGQAKYWFGKDYSNFILKDWMN 934
            ..|...||                                 |..||||.|.||||.|||:||:.|
Mosquito   806 VGSPIYLSEEERRKKQLYGGEKGAPMGDLASPQPFKNATIFELDGQAKLWIGKDYINFIVKDFTN 870

  Fly   935 LNSPFVDIIDRTTTPRMPWHDVGLCVVGTSARDVARHFIQRWNAMKLEKLRDNTRFPYLMPKSYH 999
            |:||:.|::|||||.|||||||...|:|.:|||||||||:||||:||||.|:|..||||:||||:
Mosquito   871 LDSPYADLVDRTTTVRMPWHDVATVVLGQAARDVARHFIERWNAVKLEKCRENANFPYLLPKSYN 935

  Fly  1000 QVRLNPNIQQNRQQRVTCQLLRSVSAWSCGFIEADLVEQSIHDAYIQTITKAQHYVYIENQFFIT 1064
            .:|::..........||||:|||.|:|:|||||.|.||||||:||:|||:|||||:||||||||:
Mosquito   936 DIRIDSKFLNVPLHHVTCQVLRSASSWNCGFIEPDYVEQSIHEAYVQTISKAQHYIYIENQFFIS 1000

  Fly  1065 MQLGMGVPGAYNNVRNQIGETLFKRIVRAHKERKPFRVYVIMPLLPGFEGDVGGSTGIAVRAITH 1129
            |:||..|      |:|||.|.|||||||||:|:|.|||||:||||||||||||||:||::|||||
Mosquito  1001 MELGNSV------VKNQISEYLFKRIVRAHREKKVFRVYVVMPLLPGFEGDVGGSSGISLRAITH 1059

  Fly  1130 WNYASISRGRTSILTRLQEAGIANPENYISFHSLRNHSFLNNTPITELIYVHSKLLIADDRVVIC 1194
            |||||||||::|:|.||:.|||..|.:||||||||.:|.||..|:|||||||||||||||:||||
Mosquito  1060 WNYASISRGKSSLLERLRAAGIQKPCDYISFHSLRTNSTLNGMPVTELIYVHSKLLIADDKVVIC 1124

  Fly  1195 GSANINDRSMIGKRDSEIAAILMDEEFEDGRMNGKKYPSGVFAGRLRKYLFKEHLGLLESEGSSR 1259
            |||||||||::||||||:..::.||.||:|||||:.||.||:||:|||:||:|||||||.: ..|
Mosquito  1125 GSANINDRSLLGKRDSEVCVMITDESFEEGRMNGESYPCGVYAGKLRKFLFREHLGLLEPD-PKR 1188

  Fly  1260 SDLDINDPVCEKFWHGTWRRISMQNTEIYDEVFKCIPTDFVKTFASLRKYQEEPPLAKTAPDLAA 1324
            :.:|:.|||...||:..|||.|.:||.||||||:|||:|.|::||.::::.|:..|.::.|:...
Mosquito  1189 APVDVTDPVIHTFWNDVWRRTSRRNTLIYDEVFRCIPSDNVQSFAMMKRFLEDKSLLQSNPEGIQ 1253

  Fly  1325 NRANDIQGYLVDLPLEFLNKEVLTPPGTSKEGLIPTSVWT 1364
            .....|:||||||||:||..|:||||.|||||::||.:||
Mosquito  1254 QAVERIEGYLVDLPLKFLCNEILTPPNTSKEGIMPTYMWT 1293

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Pld	NP_001137610.1	PX_PLD	230..431	CDD:132805	93/200 (47%)
		PLN02866	388..1349	CDD:215467	583/1022 (57%)
Pld	XP_061515232.1	None