DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and Sry-beta

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_001303451.1	Gene:	Sry-beta / 43570	FlyBaseID:	FBgn0003511	Length:	356	Species:	Drosophila melanogaster

Alignment Length:	366	Identity:	87/366 - (23%)
Similarity:	132/366 - (36%)	Gaps:	94/366 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    45 RLEHGDNLTDVICDLCLRRLHDARDFQRRCEHSEQVLRMRHEHWKHTVAVGDALALDDVLECLER 109
            |||...|  ...|..||..|.   ::.|...:..||.|.          :.|||     |.|  |
  Fly    49 RLELLPN--SAACRDCLEYLF---NYDRLVRNLSQVQRQ----------IADAL-----LGC--R 91

  Fly   110 EVGSLEGPMSVPLQASKPVAHVAPLMETVDFESLDFQDSSHSEHDIPSYWESSVDSGSLNTPHHQ 174
            :|   ||......||:|                       .:...:|::  ..|.:.:|..|..|
  Fly    92 QV---EGKAETKQQAAK-----------------------RARVQVPAF--KIVQATALKEPERQ 128

  Fly   175 P----ETAEL-----------FAVEPPTPPESSEEPAPDAAEKP-----------KMRRARPRQD 213
            |    |..|.           |:....:.|.|.||...:..|.|           ::.....:.|
  Fly   129 PGEEDECEEFMKEEMLDEEFQFSEPDDSMPSSEEEFFTETTEIPCHICGEMFSSQEVLERHIKAD 193

  Fly   214 NVKPKERKASGAVHPRSLHPCPECEKKFTRNFQLKLHMTAVHGMGEMRYQCEECRKNFASRHSLR 278
            ..:..|:..           |..|..|...:..|.|||....|..|:  :|..|.|.|:.:.::.
  Fly   194 TCQKSEQAT-----------CNVCGLKVKDDEVLDLHMNLHEGKTEL--ECRYCDKKFSHKRNVL 245

  Fly   279 YHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEAKPRIFECQRCSKSWPTKSDLRTHMRS 343
            .|:: ||..::.:.|..|..||.|...:.:||..|..|....|  |:.|.:.:.||...:.|:|:
  Fly   246 RHME-VHWDKKKYQCDKCGERFSLSWLMYNHLMRHDAEENALI--CEVCHQQFKTKRTYKHHLRT 307

  Fly   344 HNPNMERPFKCDRCSKAFFTRGHLNSHLLVHTG-EKPFACE 383
            |..:..| :.|..|.|:|..:..|..|..||.. |||.:.|
  Fly   308 HQTDRPR-YPCPDCEKSFVDKYTLKVHKRVHQPVEKPESAE 347

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071	11/36 (31%)
		C2H2 Zn finger	234..255	CDD:275368	7/20 (35%)
		C2H2 Zn finger	264..285	CDD:275368	5/20 (25%)
		C2H2 Zn finger	293..313	CDD:275368	7/19 (37%)
		zf-C2H2_8	305..373	CDD:292531	19/67 (28%)
		C2H2 Zn finger	324..344	CDD:275368	6/19 (32%)
		C2H2 Zn finger	354..374	CDD:275368	6/19 (32%)
		zf-H2C2_2	366..389	CDD:290200	8/19 (42%)
		C2H2 Zn finger	382..403	CDD:275368	1/2 (50%)
Sry-beta	NP_001303451.1	C2H2 Zn finger	203..223	CDD:275368	7/19 (37%)
		C2H2 Zn finger	231..251	CDD:275368	5/20 (25%)
		C2H2 Zn finger	259..308	CDD:275368	16/50 (32%)
		C2H2 Zn finger	288..303	CDD:275370	4/14 (29%)
		zf-C2H2	315..337	CDD:278523	6/21 (29%)
		C2H2 Zn finger	317..337	CDD:275368	6/19 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446672
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940