DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG30431 and CG2120

DIOPT Version :9

Sequence 1:	NP_610211.1	Gene:	CG30431 / 35549	FlyBaseID:	FBgn0050431	Length:	418	Species:	Drosophila melanogaster
Sequence 2:	NP_572446.2	Gene:	CG2120 / 31737	FlyBaseID:	FBgn0030005	Length:	315	Species:	Drosophila melanogaster

Alignment Length:	307	Identity:	76/307 - (24%)
Similarity:	111/307 - (36%)	Gaps:	102/307 - (33%)

- Green bases have known domain annotations that are detailed below.

  Fly   151 SEHDIPSYWESSVDSGSL---NTPHHQPETAELFAVEPPTPPESSEEPAPDAAEKPKMRRARPRQ 212
            ||:|:     ..:.:|:|   ||..|:|                     .|.. ||| |....::
  Fly    55 SEYDL-----LELVNGALQQRNTTEHKP---------------------TDMC-KPK-RTPTTKR 91

  Fly   213 DNVKPKERKASGAVHPRSLHPCPECEKKFTRNFQLKLH-MTAVHGMGEMRYQCEECRKNFASRHS 276
            .....|:            |.|..|:::|:..:.|::| ||..   .|..:.|.||.|.|...:.
  Fly    92 HRTTGKD------------HTCDICDRRFSEAYNLRIHKMTHT---DEKPHVCVECGKGFRQLNK 141

  Fly   277 LRYHVKSVHSTERPFGCQHCDRRFILRTQLLSHLRTHTGEAKP------------------RI-- 321
            ||.|..: |:.|||..|..|.:.|.....|..|.|.|||| ||                  ||
  Fly   142 LRIHAVT-HTAERPHKCDICGKGFRYANYLTVHRRLHTGE-KPYPCLATDCHLSFHSIHARRIHT 204

  Fly   322 ----------------------------FECQRCSKSWPTKSDLRTHMRSHNPNMERPFKCDR-- 356
                                        |.|..||:....:..|..|::.|  ..:|.|.|.:
  Fly   205 KLRHAAQTDPDPEHPLAEQEQRDTSALSFTCPVCSRVLTDQCYLSIHLKRH--YNQRDFPCPQPE 267

  Fly   357 CSKAFFTRGHLNSHLLVHTGEKPFACEYCDKCYQSVGNLNNHMVRLH 403
            |.|.||:...|..|.:.||.::||||..|...:....|...|: ::|
  Fly   268 CGKRFFSASELKHHQIAHTQQRPFACPLCPARFLRKSNHKQHL-KVH 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG30431	NP_610211.1	zf-AD	11..82	CDD:285071
		C2H2 Zn finger	234..255	CDD:275368	7/21 (33%)
		C2H2 Zn finger	264..285	CDD:275368	8/20 (40%)
		C2H2 Zn finger	293..313	CDD:275368	6/19 (32%)
		zf-C2H2_8	305..373	CDD:292531	27/117 (23%)
		C2H2 Zn finger	324..344	CDD:275368	5/19 (26%)
		C2H2 Zn finger	354..374	CDD:275368	7/21 (33%)
		zf-H2C2_2	366..389	CDD:290200	9/22 (41%)
		C2H2 Zn finger	382..403	CDD:275368	4/20 (20%)
CG2120	NP_572446.2	C2H2 Zn finger	101..121	CDD:275368	6/19 (32%)
		zf-H2C2_2	113..138	CDD:290200	10/27 (37%)
		C2H2 Zn finger	129..149	CDD:275368	8/20 (40%)
		zf-H2C2_2	142..166	CDD:290200	10/24 (42%)
		COG5048	151..>264	CDD:227381	26/115 (23%)
		C2H2 Zn finger	157..177	CDD:275368	6/19 (32%)
		C2H2 Zn finger	185..206	CDD:275368	2/20 (10%)
		C2H2 Zn finger	235..255	CDD:275368	5/19 (26%)
		C2H2 Zn finger	263..285	CDD:275368	7/21 (33%)
		C2H2 Zn finger	293..313	CDD:275368	4/20 (20%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45446585
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24409
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	2.030