Protein Alignment EcR and nhr-26

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_510119.1
• Gene: nhr-26 / 188212
• WormBaseID: WBGene00011568
• Length: 334
• Species: Caenorhabditis elegans
• Alignment Length: 426
• Identity: 80/426 - (18%)
• Similarity: 146/426 - (34%)
• Gaps: 147/426 - (34%)

  Fly   264 CLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACE---MDMYMRRKCQECRLKKCL 325
            |.||.::.:|::|...:|..||.||||::....|..|.....|.   :|. ...:|:.||..||:
 Worm     8 CKVCNEKTTGFNYGVQSCNACKMFFRRALDTPKVLKCGRDGNCPTIVLDS-GESQCRFCRFHKCI 71

  Fly   326 AVGM-------RPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEI 383
            .|||       .|..::                  :|:..                 .|..:::|
 Worm    72 IVGMIFLDAVDDPTNII------------------NKLLV-----------------MDTKRRDI 101

  Fly   384 LDLMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQ 448
              .:.|..|:..|:    ||:.::   |:.|.
 Worm   102 --FLNCTIPESLTV----DEVFSR---RSFPF--------------------------------- 124

  Fly   449 PDENESQTDVSF------RHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLR 507
             :..:..|..:|      .|::         .:.|.:.|.....:..:|.|.:.|......::|.
 Worm   125 -EPRKPGTVFNFCDWGVINHLS---------CISFIRQLDFIKFLSSQDTIAIFKYSHLMYLILV 179

  Fly   508 MARR--------YDHSSDSIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSMKVDNVEYALL 564
            .|.|        .:|......|.....|.....|.  :.::|..||  ..::..:|:.:.|:.||
 Worm   180 TAMRSYLCKEAAMNHPGKVDVFPEEAQYAAGYNKQ--LLNDIRCLL--VGRLSEIKITHEEFILL 240

  Fly   565 TAIVIFSDRPG---LEKAQ--LVEAIQSYYIDTLRIY--ILNRHCGDSMSLVFYAKLLSILTEL- 621
            :.|::.:  ||   |.|:.  ::.:.|..:...|..|  |.|..||.:.    :.::||:...:
 Worm   241 SVIILCN--PGATNLSKSGRIILASNQERFSSILLHYCLITNSKCGPAR----FNEILSLCHVVS 299

  Fly   622 RTLGN-QNAEMCFSLKLKNRKLPKFLEEIWDVHAIP 656
            |||.: .|....:||                ||.:|
 Worm   300 RTLSDLDNLTCLYSL----------------VHTVP 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	25/96 (26%)
		NR_LBD_EcR	420..652	CDD:132736	42/254 (17%)
nhr-26	NP_510119.1	ZnF_C4	8..75	CDD:197701	22/67 (33%)
		HOLI	141..301	CDD:214658	34/178 (19%)