Protein Alignment EcR and dpr-1

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_506457.2
• Gene: dpr-1 / 187759
• WormBaseID: WBGene00001062
• Length: 356
• Species: Caenorhabditis elegans
• Alignment Length: 390
• Identity: 86/390 - (22%)
• Similarity: 142/390 - (36%)
• Gaps: 115/390 - (29%)

  Fly   264 CLVCGDRAS-GYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAV 327
            ||||....: .:|:.:.||..|..||||:|:....|.||....|.:...:|..|:.||.:.||..
 Worm    16 CLVCTITENVRFHFGSTTCLACASFFRRTVSLKIQYVCKQSNNCIVSHAVRSGCRSCRFQNCLKS 80

  Fly   328 GMRPECVVPE---NQCAMKRREKKAQKE----KDKMTTSPSSQHGGNGSLASGGGQDFVKKEILD 385
            ||:...|..:   |:.....||...|.:    ::..|::..:.||            |.|:|.|:
 Worm    81 GMKTNMVRGKRDINKVPKYIRESMQQGDNMTVRNYTTSTLETLHG------------FPKQEELE 133

  Fly   386 LMTCEPPQHATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDLRRIMSQPD 450
            |           |::.::      |.|:..::.:||...|.                       |
 Worm   134 L-----------PVVKED------APNLLIVSPDQLLDYYL-----------------------D 158

  Fly   451 ENESQ-TDVSFRHITEITILTVQLIVE---FAKGLPAFTKIPQEDQITLLKACSSEVMMLRMARR 511
            .||.: ..:|..|:..:..|..|..||   ..|..|....|..||::.|::......:.|.....
 Worm   159 LNEKEPLPLSKIHLNTLGQLNQQNHVESEFICKNCPGTDLISTEDKMILIQYVKFANLWLDALWD 223

  Fly   512 YDHSSD--------------------SIFFANNRSYTRDSYKMAGMADNIEDLLHFCRQMFSMKV 556
            ..|:.|                    |.|.:|       .|:..|.        ..|    ::.:
 Worm   224 ELHAKDKQDKQNLVHCGEFADYDRLFSTFISN-------LYESVGQ--------FLC----NLNL 269

  Fly   557 DNVEYALLTAIVIFSDRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTEL 621
            |.|||:.|.:.||:       |..:|:     :..||:|.....:.|.|.:|:.|.|....:.|:
 Worm   270 DIVEYSALKSFVIW-------KLGVVD-----FSITLKIVAQEHYLGVSAALIEYYKTEKNMEEM 322

  Fly   622  621
             Worm   323  322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	29/90 (32%)
		NR_LBD_EcR	420..652	CDD:132736	45/226 (20%)
dpr-1	NP_506457.2	ZnF_C4	15..85	CDD:197701	25/68 (37%)
		HOLI	190..338	CDD:214658	33/164 (20%)