Protein Alignment EcR and nhr-268

DIOPT Version :10

• Sequence 1: NP_724460.1
• Gene: EcR / 35540
• FlyBaseID: FBgn0000546
• Length: 878
• Species: Drosophila melanogaster
• Sequence 2: NP_506902.2
• Gene: nhr-268 / 187054
• WormBaseID: WBGene00010601
• Length: 340
• Species: Caenorhabditis elegans
• Alignment Length: 399
• Identity: 82/399 - (20%)
• Similarity: 156/399 - (39%)
• Gaps: 93/399 - (23%)

  Fly   264 CLVCGDRASGYHYNALTCEGCKGFFRRSVTKSAVYCCKFGRACEMDMYMRRKCQECRLKKCLAVG 328
            ||||..||...:|..::|..||.||||:|.|:.::.||:.:.|.:......||:.||.:|||.:|
 Worm     3 CLVCSARAFNRNYGVMSCFACKMFFRRTVFKNMLFNCKYFKNCTIHYKTHPKCRACRFQKCLNIG 67

  Fly   329 MRPECVVPENQCAMKRREKKAQKEKDKMTTSPSSQHGGNGSLASGGGQDFVKKEILDLMTCEPPQ 393
            |                  ||..:.|::             ::.|..:|:...::|
 Worm    68 M------------------KAASKNDRI-------------VSIGNYEDYNFDKLL--------- 92

  Fly   394 HATIPLLPDEILAKCQARNIPSLTYNQLAVIYKLIWYQDGYEQPSEEDL---RRIMSQPDEN-ES 454
                    ::::.| ..:|     |:.....|.|       |.||.:|:   |.||...... |:
 Worm    93 --------NDLIVK-NDKN-----YSNFIDFYSL-------EDPSLKDIIEDRSIMKLVRRTPET 136

  Fly   455 QTDV-SFRHITEITILTVQLIVEFAKGLPAFTKIPQEDQITLLKACSSEVMMLRMAR-RYDHSSD 517
            ..|| .:.::...:.::..|...|.:      ::...|:.||.|...|....|.:|. .|..:..
 Worm   137 LNDVDQWSNMLAYSRISYFLDFNFIR------ELDSSDKNTLFKYNVSRAGCLALAMCAYSENKP 195

  Fly   518 SIFFANNRS-YTRDSYKMAGMADNIEDLL--HFCRQMFSMKVDNVEYALLTAIVI--------FS 571
            .:.|.|:.. :..:.|.:.|.:..:.:.:  ....:...:::...||.||..::.        ||
 Worm   196 KLTFPNDVDIFPSEMYNLCGSSTAVLNQVSGQVIAKFIELEIRQEEYLLLLLVMFCNASITNNFS 260

  Fly   572 DRPGLEKAQLVEAIQSYYIDTLRIYILNRHCGDSMSLVFYAKLLSILTELRTLGNQNAEMCFSLK 636
            .:..|    ::.:.|..|...|..|...::...:.:.  :.:|||:...:....|..:.:...::
 Worm   261 HKTKL----ILSSHQQVYCSALFRYCQLKYSKSAPTR--FTELLSVFGIVNKSVNNMSFLSMMVQ 319

  Fly   637 LKNRKLPKF 645
            ..|   |||
 Worm   320 CYN---PKF 325

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
EcR	NP_724460.1	NR_DBD_EcR	261..351	CDD:143535	30/86 (35%)
		NR_LBD_EcR	420..652	CDD:132736	45/243 (19%)
nhr-268	NP_506902.2	ZnF_C4	2..69	CDD:197701	28/83 (34%)
		HOLI	152..306	CDD:214658	28/165 (17%)