Protein Alignment Act42A and ACTR5

DIOPT Version :9

• Sequence 1: NP_523625.1
• Gene: Act42A / 35526
• FlyBaseID: FBgn0000043
• Length: 376
• Species: Drosophila melanogaster
• Sequence 2: NP_079131.3
• Gene: ACTR5 / 79913
• HGNCID: 14671
• Length: 607
• Species: Homo sapiens
• Alignment Length: 551
• Identity: 118/551 - (21%)
• Similarity: 197/551 - (35%)
• Gaps: 198/551 - (35%)

  Fly     9 LVVDNGSGMCKAGFA--GDD---APRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGIL-- 66
            ||:||||...:||:|  |.|   .||..|.::..|        |.|......|.:..:..|.|
Human    33 LVLDNGSFQVRAGWACPGQDPGPEPRLQFRAVCAR--------GRGGARGASGPQVGNALGSLEP 89

  Fly    67 ---TLKYPIEHGIVTNWDDMEKIWHHTFYNELRVAPE---EHPVLLTEAPLNPKANREKMTQIMF 125
               .|:.|.:..:..|.:..|.:..::| ..|.|:.:   :||::||||..||..:|:.|::::|
Human    90 LRWMLRSPFDRNVPVNLELQELLLDYSF-QHLGVSSQGCVDHPIVLTEAVCNPLYSRQMMSELLF 153

  Fly   126 ETFNTPAMYVAIQAVLSLY----ASGRTTGIVLDSGDGVSHTVPIYEGYALPHAILRLDLAGRDL 186
            |.:..|.:...|.::.|.|    .:...:|:::.||...:|.:||.||........|::|.|...
Human   154 ECYGIPKVAYGIDSLFSFYHNKPKNSMCSGLIISSGYQCTHVLPILEGRLDAKNCKRINLGGSQA 218

  Fly   187 TDYLMKILTER--GYSFTTTAEREIVRDIKEKLCYVALDFEQEM--------------------- 228
            ..||.::|..:  |:....|..|  :.:|..:..|:|.|:.:|:
Human   219 AGYLQRLLQLKYPGHLAAITLSR--MEEILHEHSYIAEDYVEELHKWRCPDYYENNVHKMQLPFS 281

  Fly   229 -----ATAASSSSLEKSYE---------------------------------LPDGQV------- 248
                 :|..|....|:..:                                 |.|||:
Human   282 SKLLGSTLTSEEKQERRQQQLRRLQELNARRREEKLQLDQERLDRLLYVQELLEDGQMDQFHKAL 346

  Fly   249 ----------------------------------------------------------------- 248
                                                                             
Human   347 IELNMDSPEELQSYIQKLSIAVEQAKQKILQAEVNLEVDVVDSKPETPDLEQLEPSLEDVESMND 411

  Fly   249 ------------------------------ITIGNERFRCPESLFQPSFLGMEACGIHETTYNSI 283
                                          :.:|.||.|.||.:||||.:|.|..||.||....:
Human   412 FDPLFSEETPGVEKPVTTVQPVFNLAAYHQLFVGTERIRAPEIIFQPSLIGEEQAGIAETLQYIL 476

  Fly   284 MKCDVDIRKDLYANTVLSGGTTMYPGIADRMQKEITALAP--STMKIKIVAPPERKYSVWIGGS- 345
            .:...||::.|..|..|:||.|||||:..||:||:..:.|  |:.::::.:.|  ....|.|..
Human   477 DRYPKDIQEMLVQNVFLTGGNTMYPGMKARMEKELLEMRPFRSSFQVQLASNP--VLDAWYGARD 539

  Fly   346 -ILASLSTFQQMWISKQEYDESGPSIVHRKC 375
             .|..|.. .::||:::||:|.|...:...|
Human   540 WALNHLDD-NEVWITRKEYEEKGGEYLKEHC 569

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Act42A	NP_523625.1	PTZ00281	1..376	CDD:173506	118/551 (21%)
ACTR5	NP_079131.3	COG5277	32..569	CDD:227602	117/549 (21%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	584..607

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910