Protein Alignment CG10417 and PPM1B

DIOPT Version :9

• Sequence 1: NP_610169.1
• Gene: CG10417 / 35492
• FlyBaseID: FBgn0033021
• Length: 662
• Species: Drosophila melanogaster
• Sequence 2: XP_016859884.1
• Gene: PPM1B / 5495
• HGNCID: 9276
• Length: 487
• Species: Homo sapiens
• Alignment Length: 648
• Identity: 150/648 - (23%)
• Similarity: 211/648 - (32%)
• Gaps: 298/648 - (45%)

  Fly     1 MGAYLSHPKTDKTSTDQFNELLAVGASSMQGWRNSQEDAHNSILNFDN---NTSFFAVYDGHGGA 62
            |||:|..|||:|.:.......|..|.|||||||...||||.:::...:   :.|||||||||.|:
Human     1 MGAFLDKPKTEKHNAHGAGNGLRYGLSSMQGWRVEMEDAHTAVVGIPHGLEDWSFFAVYDGHAGS 65

  Fly    63 EVAQYCADKLPHFLKNLETYKNGQFEVALKEAFLGFDKTLLDPSIVSILKILAGEHNFVDAEADD 127
            .||.||:   .|.|:::.|
Human    66 RVANYCS---THLLEHITT---------------------------------------------- 81

  Fly   128 YEEEDLAELQEESNLPLNEVLEKYKGLPQKKDLDLKSSDHKENFKMRSPYFRGRRAAALAAEATN 192
                                                    .|:|          |||
Human    82 ----------------------------------------NEDF----------RAA-------- 88

  Fly   193 KAVMDPSAKPDGSSTSAAAAAAALSADGVANSRNPSNVVNPMAGADSNTTTSINDLSTKNAALKD 257
                       |.|.|    |..||.:.|.|                         ..:...||.
Human    89 -----------GKSGS----ALELSVENVKN-------------------------GIRTGFLKI 113

  Fly   258 DSVNDQNEGSNGTDFKHTLVSSSNKKLFATGSNDMTELNQSSKNEFTNSSTSKEFERNINSSQDD 322
            |                                                    |:.||
Human   114 D----------------------------------------------------EYMRN------- 119

  Fly   323 EFTDDDADYEENDNVKSPDTSSAESSDCTENDDDGDEDGNEDSDEEETDEDQMANDNFCANMIEE 387
             |:|                                                :.|
Human   120 -FSD------------------------------------------------LRN---------- 125

  Fly   388 PGKD-SGCTAVVCLLQGRDLYVANAGDSRCVISRSGQAIEMSIDHKPEDDEEASRIIKAGGRVTL 451
             |.| ||.|||..::..:.:|..|.||||.|:.|:||....:.||||.:..|..||..|||.|.:
Human   126 -GMDRSGSTAVGVMISPKHIYFINCGDSRAVLYRNGQVCFSTQDHKPCNPREKERIQNAGGSVMI 189

  Fly   452 DGRVNGGLNLSRALGDHAYKTNVTLPAEEQMISALPDIKKLIITPEDEFMVLACDGIWNYMSSEE 516
            . ||||.|.:||||||:.||........||::|..|::.:::...||||::|||||||:.||:||
Human   190 Q-RVNGSLAVSRALGDYDYKCVDGKGPTEQLVSPEPEVYEILRAEEDEFIILACDGIWDVMSNEE 253

  Fly   517 VVEFVRCRLKDNKKLSTICEELFDNCLAPNTMGDGTGCDNMTAVIVQFKKKLQELQSTIPPNQTE 581
            :.|:|:.||:.:..|..:|..:.|.||...:.      |||:.|:|.|..         .|..::
Human   254 LCEYVKSRLEVSDDLENVCNWVVDTCLHKGSR------DNMSIVLVCFSN---------APKVSD 303

  Fly   582 DKLLKTSENVSHSLNDQSASKRCASQNADADDEILEKNNSK------RLKTDLEQENIKDRTP 638
            :.:.|.||      .|:....|..........||:||:..:      .:...|..|||.:..|
Human   304 EAVKKDSE------LDKHLESRVEGTFFKKPTEIMEKSGEEGMPDLAHVMRILSAENIPNLPP 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG10417	NP_610169.1	PP2Cc	18..>100	CDD:214625	30/84 (36%)
		PP2Cc	<374..564	CDD:238083	75/190 (39%)
PPM1B	XP_016859884.1	None

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0631
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D957254at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100270
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.720