Protein Alignment Ir40a and grin3a

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_073770471.1
• Gene: grin3a / 564832
• ZFINID: ZDB-GENE-130530-780
• Length: 1117
• Species: Danio rerio
• Alignment Length: 773
• Identity: 153/773 - (19%)
• Similarity: 255/773 - (32%)
• Gaps: 287/773 - (37%)

  Fly    10 LPYLLGLLNSTRLTFIGNDESDTAI--ALTQIVRGLQQSSLAILALPSLALSDGVCQKERNVYLD 72
            ||  :|||...|:   |....|..:  ||..:.|.:  .|.|.:: |.|||..|.         .
Zfish   374 LP--MGLLAHGRM---GEPSLDHYVQDALELVARAV--GSAATVS-PQLALIPGT---------T 421

  Fly    73 DFLQRLHRSNYKSVVFSQTELFFQHIEENLQGANECISL-----ILDEPNQLLNSLHDRHLGHRL 132
            :.|.||...|..|..|....:    ...:..|.:.|||:     |:.|.:..:.:|....:|..:
Zfish   422 NCLARLEAKNLTSGTFLSRYM----ASTSFDGLSGCISVQEESTIISESHHFIWNLQHDPIGKPM 482

  Fly   133 SLFIFYW--------------------GARWPPSSRVIRFREPLRVV-VVTRPRKKAFRIYYNQA 176
            ...:..|                    ||.|..|||:     .|||| :|..|
Zfish   483 WTRLGSWKHGKVVMDYGVWPNKRRSQPGADWRHSSRL-----HLRVVTLVEHP------------ 530

  Fly   177 RPCSDSQLQLVNWYDGDNLGL---QRIPLLP----TAL--SVYANFKGRTFRVPVFHSPPWFWVT 232
                     .|...|.|:.||   .::.|.|    |||  |::...:|....||:......:  .
Zfish   531 ---------FVFTRDVDDEGLCPAGQLCLDPLTNDTALLESLFQGLQGANDTVPLEFKKCCY--G 584

  Fly   233 YCNNSFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFK-YIEAPGRTQGSMRSEDGK 296
            ||            :|.:||                |::.|.|.|. ||...|:.        |.
Zfish   585 YC------------IDLLEK----------------LAEDMGFDFDLYIVGDGKY--------GA 613

  Fly   297 DSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFS--FF------------TLADSGAFATH 347
            ..|..:||.:|.|.||.|...:....::..|.:.|:|:  ||            |.|..|||
Zfish   614 YKNGRWTGLVGDLMSGAAHLAVTSFSINSARSQVIDFTSPFFSTSLGILVRTRDTAAPIGAF--- 675

  Fly   348 APRRLNEALAIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIWRR------RWANSDVEHLGEL 406
                       |.|....:|..:.:::..:. :|..:    |.|:.      |..|.|.......
Zfish   676 -----------MWPLHWSMWLGIFVSLHVTA-VFLTL----YEWKSPFGMTPRGRNRDRVFSFSS 724

  Fly   407 YIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCNELHNGYRAKFLTIVY 471
            .:::.| ..:..|...:||              .||                   :..:||..::
Zfish   725 ALNVCY-AILFGRTAAIKP--------------PKC-------------------WTGRFLMNLW 755

  Fly   472 WIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHD--------GYRLYVEKESSSLEM 528
            .|...:.|: .|:|.|.:.....      .|.::|..  |||        |:|....:|||:.:.
Zfish   756 AIFCLFCLS-TYTANLAAVMVGE------KTYEQLSG--IHDPKLHHPSQGFRFGTVRESSAEDY 811

  Fly   529 LENGTELFRQLYALMRQ-----------QVINDPQ---GFFID--------SVEAGIKLIAEGGE 571
            ::..   |.:::..||:           .:.:|||   .|.:|        |::|..|::..|..
Zfish   812 VKKS---FPEMHEYMRRYNAPTTPDGIDHLKDDPQKLDAFIMDKALLDYEVSIDADCKMLTVGKP 873

  Fly   572 DKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMT 636
                        |.::.||                :.::...|...:::.::.|....|.:|.:
Zfish   874 ------------FAIEGYG----------------IGLKQNSPLTSNISELVSQYKSDGFMDML- 909

  Fly   637 AAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVG 694
               :.|.|:.|..         .|.|.|.:.|        ..:.::...|.|:.|.||
Zfish   910 ---HDKWYKVVPC---------GKRSFAVTET--------LQMGIKHFSGLFVMLCVG 947

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	19/73 (26%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	23/107 (21%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	29/170 (17%)
grin3a	XP_073770471.1	None