Protein Alignment Ir40a and grik1b

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_690040.5
• Gene: grik1b / 561540
• ZFINID: ZDB-GENE-070821-1
• Length: 906
• Species: Danio rerio
• Alignment Length: 525
• Identity: 96/525 - (18%)
• Similarity: 192/525 - (36%)
• Gaps: 117/525 - (22%)

  Fly   219 RVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVTG-----------------GRDH--- 263
            ::.|::|.....:|..|    :|:..|..||:..|.:.||.                 |.|.
Zfish   442 KIGVWNSNTGLNLTDSN----KDKNTNVTDSMANRTLIVTTILENPYVMYKKSDKPLYGNDRFEG 502

  Fly   264 ---RLLMLLSKHMNFRFKYIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSW 325
               .||..||..:.|.:   |....|.|...:::.|   ..:.|.:..|....||..:..:.:::
Zfish   503 YCLDLLKELSNILGFSY---EVKLVTDGKYGAQNDK---GEWNGMVRELIDHVADLAVAPLTITY 561

  Fly   326 ERRKAIEFS--FFTLADSGAFATHAPRRLNEAL-AIMRPFKQDIWPHLILTIIFSGPIFYGIIA- 386
            .|.|.|:||  |.||..|..:  |.|...|..: :.:.|...|||.:::|..:....:.: :||
Zfish   562 VREKVIDFSKPFMTLGISILY--HKPNGTNPGVFSFLNPLSPDIWMYVLLACLGVSCVLF-VIAR 623

  Fly   387 -LPYIW-RRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRL 449
             .||.| .....|.|.:.:...:                   |::::           :||.:..
Zfish   624 FTPYEWYNPHPCNPDSDVVENNF-------------------TLINS-----------VWFGVGA 658

  Fly   450 FLKQSCNELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPAREPPINTLQ------RLQA 508
            .::|....:......:.:..::|. .|.::...|:|.|.:.......:.||::..      :::.
Zfish   659 LMQQGSELMPKALSTRIVGGIWWF-FTLIIISSYTANLAAFLTVERMDSPIDSADDLAKQTKIEY 722

  Fly   509 AMIHDGYRLYVEKESSSLEMLENGTELFRQLYALMRQQVINDPQGFFIDSVEAGIKLIAEGGEDK 573
            ..:.||..:...|:|.        ...:.:::|.|..:    .....:.:...||:.:..  .|.
Zfish   723 GAVRDGSTMTFFKKSK--------ISTYEKMWAFMSSR----KNTALVKNNREGIQRVLT--TDY 773

  Fly   574 AVLGGRETLFFNVQQYGSNNFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAA 638
            |:|....::.: :.|...|..|:...:.::...|...||.|:...:...::||.|.|.|..|
Zfish   774 ALLMESTSIEY-ISQRNCNLTQIGGLIDSKGYGVGTPIGSPYRDKVTIAILQLQEEGKLHMM--- 834

  Fly   639 EYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLAAGVILL 703
                      ..:.::|          :.....||...|.|.:..:.|.||.|..|.:.:..:.:
Zfish   835 ----------KEKWWRG----------NGCPEEDSKEASALGVENIGGIFIVLAAGLVLSVFVAI 879

  Fly   704 LEIVF 708
            .|.::
Zfish   880 GEFIY 884

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	18/72 (25%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	25/98 (26%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	26/146 (18%)
grik1b	XP_690040.5	PBP1_iGluR_Kainate	65..456	CDD:380605	2/13 (15%)
		Periplasmic_Binding_Protein_Type_2	471..840	CDD:473866	77/436 (18%)