Protein Alignment Ir40a and grin2da

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: XP_073787594.1
• Gene: grin2da / 449864
• ZFINID: ZDB-GENE-041008-124
• Length: 1918
• Species: Danio rerio
• Alignment Length: 620
• Identity: 122/620 - (19%)
• Similarity: 200/620 - (32%)
• Gaps: 208/620 - (33%)

  Fly   142 RWPPSSRVIRFREP------LRVV-------VVTRPRKKAFRIYYNQARPCSDSQLQLVNWYDGD 193
            |:||.||...|.:|      ||||       |:..|...........:.||
Zfish   435 RYPPWSRYGPFLKPLDDSQHLRVVTLEERPFVIVEPADPGTGSCIRDSVPC-------------- 485

  Fly   194 NLGLQRIPLLPTALSVYANFKGRTFRVPVFHSPPWFWVTYCNNSFEEDEEFNSLDSIEKRKVRVT 258
                 |:||...:..|....:.               :.:|...|..|
Zfish   486 -----RLPLNNRSSMVVEGIQS---------------MKHCCKGFCID----------------- 513

  Fly   259 GGRDHRLLMLLSKHMNFRFK-YIEAPGRTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVG 322
                  :|..|:|.:.|.:. |:...||        .||:.:..:.|.:|.:.|.:||..:|.:.
Zfish   514 ------VLKRLAKIVGFTYDLYLVTNGR--------HGKNIDGQWNGMVGEVVSKRADMAIGSLT 564

  Fly   323 LSWERRKAIEFSF------FTLADSGAFATHAPRRLNEALAIMRPFKQDIWPHLI---LTII--- 375
            ::.||.:.:|||.      .::..|.:..|.:|.      |.:.|:...:|..:.   |:::
Zfish   565 INEERSEVVEFSVPFVETGISVMVSRSNGTVSPS------AFLEPYSPAVWVMMFVMCLSVVAVT 623

  Fly   376 -----FSGPIFYGIIALPYIWRRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLSAHQMP 435
                 |..|:.|.                                          |::.|.....
Zfish   624 VFIFEFFSPVGYN------------------------------------------RSLQSGKTAG 646

  Fly   436 HQLFQ--KCIWFTLRLFLKQSCN-ELHNGYRAKFLTIVYWIAATYVLADVYSAQLTSQFARPARE 497
            ...|.  |.||....|....|.. |...|..:|.:.:|:...|...||. |:|.|.   |...:|
Zfish   647 GSKFTIGKSIWLLWALVFNNSVPVENPRGTTSKIMVLVWAFFAVIFLAS-YTANLA---AFMIQE 707

  Fly   498 PPINTLQRLQAAMIHDGYRLYVEKESSSLEMLENGT--ELFRQLYALMRQQVI-NDPQGFFIDSV 559
            ..|:|:..|...........|......:   :.||:  |..|..|..|.|.:: |:.:|     |
Zfish   708 EYIDTVSGLSDKKFQHPTEQYPPLRFGT---VPNGSTEENIRSNYPNMHQYMVRNNQRG-----V 764

  Fly   560 EAGIKLIAEGG-----EDKAVLG--GRETLFFNVQQYGSNNFQLSQKLY--TRYSAVAVQIGCPF 615
            |..|:.:..|.     .|.|||.  .|:.....|...||.      |::  |.| .||:.....:
Zfish   765 EDAIENLKTGKLDAFIYDAAVLNYMARKDEGCKVMTIGSG------KVFATTGY-GVALHKNSRW 822

  Fly   616 LGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTESYDSTVISPLN 680
            ...|:..|:||.....:|.:              .|::...: ..|.:.        ..:.|.|:
Zfish   823 KRPLDLALLQLVGDDEIDML--------------ERLWLSGI-CHNDKI--------EVMSSKLD 864

  Fly   681 LRMLQGAFIALGVGSLAAGVILLL----EIVFIKL 711
            :..:.|.|..|.|   |.|:.||:    .:|:.||
Zfish   865 IDNMAGVFYMLLV---AMGLSLLVFAWEHLVYWKL 896

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	20/77 (26%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	21/110 (19%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	36/152 (24%)
grin2da	XP_073787594.1	None