Protein Alignment Ir40a and GluRIID

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_651982.1
• Gene: GluRIID / 44483
• FlyBaseID: FBgn0028422
• Length: 902
• Species: Drosophila melanogaster
• Alignment Length: 762
• Identity: 151/762 - (19%)
• Similarity: 266/762 - (34%)
• Gaps: 217/762 - (28%)

  Fly    20 TRLTFIGNDESDTAIALTQIVRGLQQSSLAILALPSLALSDGVCQKERNVYLDDFLQRLHRSNYK 84
            :|:..:|   |.|.:|  :::|..||..:               ..|...|:...| .||
  Fly   211 SRIVVVG---STTGVA--ELLRQAQQVGI---------------MNEDYTYIIGNL-NLH----- 249

  Fly    85 SVVFSQTELFFQHIEENLQGANECISLILDEPNQLLNSLHDRHLG-----HRLSLFIFYWGARWP 144
              .|...|  :::.|.|:.|. ...|...:|...|:..|| :.||     :..|.||....|...
  Fly   250 --TFDLEE--YKYSEANITGI-RMFSPDQEEVRDLMEKLH-QELGESEPVNSGSTFITMEMALTY 308

  Fly   145 PSSRVI----------------------------RFREPLRVVVVTRPRKKAF--RIYY--NQAR 177
            .:.|||                            .||..:|.:.:   ::|..  |||:  |..:
  Fly   309 DAVRVIAETTKHLPYQPQMLNCSERHDNVQPDGSTFRNYMRSLEI---KEKTITGRIYFEGNVRK 370

  Fly   178 PCSDSQLQLV--------NWYDGDNLGLQRIPLLPTALSVYANFK--------GRTFRVPV-FHS 225
            ..:...::|.        .|.:|.:...||.|..       .||.        .:||.|.: ..:
  Fly   371 GFTFDVIELQTSGLVKVGTWEEGKDFEFQRPPQA-------VNFNDIDDGSLVNKTFIVLISVAT 428

  Fly   226 PPWFWVTYC------NNSFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPG 284
            .|:..:...      ||.|:                    |....|:..|:..:.|.|.:.:. |
  Fly   429 KPYASLVESIDTLIGNNQFQ--------------------GYGVDLIKELADKLGFNFTFRDG-G 472

  Fly   285 RTQGSMRSEDGKDSNDSFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFS--FFTLADSGAFATH 347
            ...||...     :.:|.:|.:..:..|:||..:.|:.::.||.:.|:||  |..|..:..:.
  Fly   473 NDYGSFNK-----TTNSTSGMLKEIVEGRADLAITDLTITSEREEVIDFSIPFMNLGIAILYV-- 530

  Fly   348 APRRLNEAL-AIMRPFKQDIWPHLILTIIFSGPIFYGIIALPYIWRR----RWAN--SDVEHLGE 405
            .|::...|| :.|.||..::|       ::.|..:.|:....:|..|    .|.|  ..:|...|
  Fly   531 KPQKAPPALFSFMDPFSSEVW-------LYLGIAYLGVSLCFFIIGRLSPIEWDNPYPCIEEPEE 588

  Fly   406 LYIHMTYLKEITPRLLKLKPRTVLSAHQMPHQLFQKCIWFTLRLFLKQSCNELHNGYRAKFLTIV 470
            |....|                           ....:|||....|:|...........:.::.:
  Fly   589 LENQFT---------------------------INNSLWFTTGALLQQGSEIAPKALSTRTISAI 626

  Fly   471 YWIAATYVLADVYSAQLTSQFARPAREPPINTLQRLQAAMIHDGYRLYVEKESSSLEMLENGTEL 535
            :|. .|.::...|:|.|.:.........|||:::.|  |...|..:...::..|:........|
  Fly   627 WWF-FTLIMVSSYTANLAAFLTIENPTSPINSVKDL--ADNKDDVQYGAKRTGSTRNFFSTSEE- 687

  Fly   536 FRQLYALMRQQ--------VINDPQGFFIDSVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYGSN 592
              .:|..|.:.        :.|:.||  :|.|::|.|.        |.|....::.||..: ..|
  Fly   688 --PIYIKMNEYLNAHPEMLMENNQQG--VDKVKSGTKY--------AFLMESTSIEFNTVR-ECN 739

  Fly   593 NFQLSQKLYTRYSAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSV 657
            ..::...|..:...:|:....|:....|..|::|.|.|:|.::.    .|.:.||.|     |..
  Fly   740 LTKVGDPLDEKGYGIAMVKNWPYRDKFNKALLELQEQGVLARLK----NKWWNEVGA-----GVC 795

  Fly   658 QAKNSEAYSRTESYDSTVISPLNLRMLQGAFIALGVGSLAAGVILLL 704
            .||:          |....|.|.:..|.|.::.|.:||:.:.:|.:|
  Fly   796 SAKS----------DDDGPSELGVDNLSGIYVVLVIGSIISIIISIL 832

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	18/72 (25%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	22/96 (23%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	31/148 (21%)
GluRIID	NP_651982.1	PBP1_iGluR_Kainate	35..400	CDD:380605	43/223 (19%)
		PBP2_iGluR_Kainate	417..788	CDD:270432	87/453 (19%)
		Lig_chan	547..819	CDD:459656	64/341 (19%)