Protein Alignment Ir40a and Ir84a

DIOPT Version :10

• Sequence 1: NP_610140.4
• Gene: Ir40a / 35449
• FlyBaseID: FBgn0259683
• Length: 732
• Species: Drosophila melanogaster
• Sequence 2: NP_649720.2
• Gene: Ir84a / 40891
• FlyBaseID: FBgn0037501
• Length: 644
• Species: Drosophila melanogaster
• Alignment Length: 752
• Identity: 139/752 - (18%)
• Similarity: 260/752 - (34%)
• Gaps: 217/752 - (28%)

  Fly    34 IALTQIVRGLQQSSLAILALPSLALSDGVCQKERNVYLDDFLQRLHRS----------------- 81
            |.||..:|.||..|:....|...|             .:|||:..|.|
  Fly    14 IILTAFLRVLQIESINTNFLELAA-------------FEDFLRSEHLSHVLVVRGDDADGDWKIE 65

  Fly    82 -------NYKSVVFSQTELFFQHIEENLQGANECISLILDEPNQLLN------SLHDRHLGHRLS 133
                   ||: |.|.:.|:.....:....|:.....|:|:..:.|:.      :....:..:.|:
  Fly    66 CHQKLLANYR-VQFYRPEMSANFEDLMFYGSPRTAVLVLNSEHVLVRRQVFGVASEAGYFNNSLA 129

  Fly   134 LFIFYWGARWPPSSRVI-------RFREPLRVVVVTRPRKKAFRIYYNQARPCSDSQLQLV---- 187
            .||...|....|..::|       |......:.|..|....|..::|:..|....:...|:
  Fly   130 WFILGSGRESLPVEQLIDQLLSGYRMGIDADITVALRGPDNASMLFYDVYRISRQANTPLIIEKK 194

  Fly   188 -NW-YDGDNLGLQRIPLLPTALSVYANFKG------RTF-RVPVFHS------PPWFW-VTYCNN 236
             .| :.|   |.|:          :.|||.      |.| .|.:..|      ||.|. :.|
  Fly   195 GLWTHSG---GYQK----------FGNFKNTWVIRRRNFLNVTLIGSTVLTEKPPGFGDMEY--- 243

  Fly   237 SFEEDEEFNSLDSIEKRKVRVTGGRDHRLLMLLSKHMNFRFKYIEAPGRTQGSMRSEDGK-DSND 300
             ..:|::...||.:::        :.::|..|:.:..|.....         |:..:.|: ..|.
  Fly   244 -LADDKQLQQLDPMQR--------KTYQLFQLVERMFNLSLAI---------SLTDKWGELLDNG 290

  Fly   301 SFTGGIGLLQSGQADFFLGDVGLSWERRKAIEFSFFTLADSGAFATHAPRRLNEALAIMRPFKQD 365
            |::|.:|.:.|.:|||.:..:....:|:..:::|......:..|....|||.:.......|....
  Fly   291 SWSGVMGQVTSREADFAVCPIRFVLDRQPYVQYSAVLHTQNIHFLFRHPRRSHIKNIFFEPLSNQ 355

  Fly   366 IWPHLILTIIFSGPIFYGIIALPYIWRRRWANSDVEHLGELYIHMTYLKEITPRLLKLKPRTVLS 430
            :| ..:|.::....|.                        |..|:        ||.::     ||
  Fly   356 VW-WCVLALVTGSTIL------------------------LLFHV--------RLERM-----LS 382

  Fly   431 AHQMPHQLFQKCIWFT-LRLFLKQS-CNELHNGYRAKFLTIVYWIAATYVLADVYSA----QLTS 489
              .|.::.  ..:||| |..:|:|. .||:...:..:.|..:..| .:::|...|.|    .|.|
  Fly   383 --NMENRF--SFVWFTMLETYLQQGPANEIFRLFSTRLLISLSCI-FSFMLMQFYGAFIVGSLLS 442

  Fly   490 QFARPAREPPINTLQRLQAAMIHDGYRLYVEKESSSLEMLEN-GTELFRQLYALM-----RQQVI 548
            :.||        ::..|| |:......:.:|..|.:..:..| ..:|.|.:|...     ...::
  Fly   443 ESAR--------SIVNLQ-ALYDSNLAIGMENISYNFPIFTNTSNQLVRDVYVKKICKSGEHNIM 498

  Fly   549 NDPQG---------FFIDSVEAGIKLIAEGGEDKAVLGGRETLFFNVQQYGSNNFQLSQKLYTRY 604
            :..||         .|..:::...:|:.|...|:|.....:.:.||: .|.|.:
  Fly   499 SLQQGAERIIQGRFAFHTAIDRMYRLLLELQMDEAEFCDLQEVMFNL-PYDSGS----------- 551

  Fly   605 SAVAVQIGCPFLGSLNNVLMQLFESGILDKMTAAEYAKQYQEVEATRIYKGSVQAKNSEAYSRTE 669
               .:..|.|:...|.:.|:....:|:|          ||.:      .|..|:..:...:..::
  Fly   552 ---VMPKGSPWREHLAHALLHFRATGLL----------QYND------KKWMVRRPDCSLFKTSQ 597

  Fly   670 SYDSTVISPLNLRMLQGAFIALGVGSLAAGVILLLEI 706
                   :.::|.....|..||.:..:|:.::.|||:
  Fly   598 -------AEVDLEHFAPALFALALAMVASALVFLLEL 627

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ir40a	NP_610140.4	Lig_chan-Glu_bd	<265..336	CDD:463166	15/71 (21%)
		Periplasmic_Binding_Protein_Type_2	297..>391	CDD:473866	18/93 (19%)
		Periplasmic_Binding_Protein_Type_2	<496..637	CDD:473866	26/155 (17%)
Ir84a	NP_649720.2	ATP-sulfurylase	<54..>112	CDD:460310	9/58 (16%)
		Periplasmic_Binding_Protein_Type_2	<282..>355	CDD:473866	16/72 (22%)
		Lig_chan	353..602	CDD:459656	57/338 (17%)